Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   NYE32_RS04575 Genome accession   NZ_CP150201
Coordinates   935178..935885 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus sp. FSL R7-0248     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 930178..940885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS04550 (NYE32_04550) - 930948..931715 (-) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -
  NYE32_RS04555 (NYE32_04555) - 931904..932554 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  NYE32_RS04560 (NYE32_04560) - 932566..933264 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  NYE32_RS04565 (NYE32_04565) - 933282..934115 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  NYE32_RS04570 (NYE32_04570) - 934125..934892 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  NYE32_RS04575 (NYE32_04575) vicR 935178..935885 (+) 708 WP_002884978.1 response regulator YycF Regulator
  NYE32_RS04580 (NYE32_04580) vicK 935878..937218 (+) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NYE32_RS04585 (NYE32_04585) vicX 937224..938036 (+) 813 WP_339157105.1 MBL fold metallo-hydrolase Regulator
  NYE32_RS04590 (NYE32_04590) - 938096..938455 (+) 360 WP_037597735.1 YbaN family protein -
  NYE32_RS04595 (NYE32_04595) - 938507..939721 (-) 1215 WP_339157106.1 aminoacyltransferase -
  NYE32_RS04600 (NYE32_04600) yidA 939723..940532 (-) 810 WP_339157107.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=966166 NYE32_RS04575 WP_002884978.1 935178..935885(+) (vicR) [Streptococcus sp. FSL R7-0248]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=966166 NYE32_RS04575 WP_002884978.1 935178..935885(+) (vicR) [Streptococcus sp. FSL R7-0248]
ATGAAAAAAATTCTAGTAGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAAGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAGGAAAGTTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCGTTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387

Multiple sequence alignment