Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   NYE32_RS04580 Genome accession   NZ_CP150201
Coordinates   935878..937218 (+) Length   446 a.a.
NCBI ID   WP_013990681.1    Uniprot ID   -
Organism   Streptococcus sp. FSL R7-0248     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 930878..942218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS04550 (NYE32_04550) - 930948..931715 (-) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -
  NYE32_RS04555 (NYE32_04555) - 931904..932554 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  NYE32_RS04560 (NYE32_04560) - 932566..933264 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  NYE32_RS04565 (NYE32_04565) - 933282..934115 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  NYE32_RS04570 (NYE32_04570) - 934125..934892 (-) 768 WP_038675884.1 amino acid ABC transporter ATP-binding protein -
  NYE32_RS04575 (NYE32_04575) vicR 935178..935885 (+) 708 WP_002884978.1 response regulator YycF Regulator
  NYE32_RS04580 (NYE32_04580) vicK 935878..937218 (+) 1341 WP_013990681.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NYE32_RS04585 (NYE32_04585) vicX 937224..938036 (+) 813 WP_339157105.1 MBL fold metallo-hydrolase Regulator
  NYE32_RS04590 (NYE32_04590) - 938096..938455 (+) 360 WP_037597735.1 YbaN family protein -
  NYE32_RS04595 (NYE32_04595) - 938507..939721 (-) 1215 WP_339157106.1 aminoacyltransferase -
  NYE32_RS04600 (NYE32_04600) yidA 939723..940532 (-) 810 WP_339157107.1 sugar-phosphatase -
  NYE32_RS04605 (NYE32_04605) - 940711..941568 (+) 858 WP_339157108.1 GNAT family N-acetyltransferase -
  NYE32_RS04610 (NYE32_04610) - 941661..942047 (+) 387 WP_073686299.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50929.21 Da        Isoelectric Point: 5.1606

>NTDB_id=966167 NYE32_RS04580 WP_013990681.1 935878..937218(+) (vicK) [Streptococcus sp. FSL R7-0248]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=966167 NYE32_RS04580 WP_013990681.1 935878..937218(+) (vicK) [Streptococcus sp. FSL R7-0248]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAACAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAATGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGCTT
TATCTCAGGTCTGGTTGCCGTTCTTCATGATGCTACTGAGCAGGAAAAAGAAGAGCGTGAACGCCGTCTCTTTGTATCAA
ACGTTAGTCATGAGTTACGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGATGAA
GAGATTGCTCCTAACTTTATCAAAGTCTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCACGTATTGATAATAAGAGTACTCAACTTGATGTTGAAATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATCGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTCTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657

Multiple sequence alignment