Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NYE32_RS01280 Genome accession   NZ_CP150201
Coordinates   242877..243776 (+) Length   299 a.a.
NCBI ID   WP_037598985.1    Uniprot ID   A0A6N3A9D2
Organism   Streptococcus sp. FSL R7-0248     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 237877..248776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS01260 (NYE32_01260) trkA 239041..240390 (-) 1350 WP_037598979.1 Trk system potassium transporter TrkA -
  NYE32_RS01265 (NYE32_01265) - 240668..241177 (+) 510 WP_002886541.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NYE32_RS01270 (NYE32_01270) - 241488..242045 (+) 558 WP_037598980.1 ECF transporter S component -
  NYE32_RS01275 (NYE32_01275) - 242048..242698 (+) 651 WP_037598982.1 phosphatase PAP2 family protein -
  NYE32_RS01280 (NYE32_01280) comR 242877..243776 (+) 900 WP_037598985.1 helix-turn-helix transcriptional regulator Regulator
  NYE32_RS01285 (NYE32_01285) comA 243951..246047 (+) 2097 WP_037598988.1 peptide cleavage/export ABC transporter Regulator
  NYE32_RS01290 (NYE32_01290) - 246158..246490 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  NYE32_RS01295 (NYE32_01295) - 246541..247932 (-) 1392 WP_037598995.1 DUF4153 domain-containing protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35213.65 Da        Isoelectric Point: 5.3732

>NTDB_id=966147 NYE32_RS01280 WP_037598985.1 242877..243776(+) (comR) [Streptococcus sp. FSL R7-0248]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDKLSYIAKRLGKNMTDLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKAKLALIEEVYEKFFELLPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIVKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKEAAENYDKAIMFASVLEDSVLEESIRAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=966147 NYE32_RS01280 WP_037598985.1 242877..243776(+) (comR) [Streptococcus sp. FSL R7-0248]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAGCAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGTCAGTTAATTCGCATTGAAAAAGGGGAGTCGCTCCCGTCTTTGGATAAATTATCTT
ATATTGCAAAACGTCTAGGAAAAAATATGACCGATTTATTGGATCATGATAATATTACTATCCCTGACGAATACTACGAG
ATGAAGAATCGTCTGATTAAGTTTCCAACGTATAGAAATCCAGAAAGAATAAAGGCTAAACTTGCCTTAATTGAGGAGGT
CTATGAGAAATTCTTTGAACTTCTCCCAGAAGAAGAATTGTTAACTCTAGATATTTTGGAAAATATTTTGAGTTTTACTA
GTTGGGAAGAGAGTCCTAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTTATTGACTACTATTTCTTCCATCTTTATGGAAGAAAACAGTATGACAAAAAACTTTTTGAAAGAAT
CGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGACGTCTATAATATTGTTTTGTTTAATGATTTGATGGCTATCG
CTGCTTTGAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCCAAATATGAACTTCTTCATAAAGGAAACAAGAAAGAGGC
TGCAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAGAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N3A9D2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

99.331

100

0.993
  comR Streptococcus salivarius SK126

98.662

100

0.987
  comR Streptococcus thermophilus LMG 18311

95.318

100

0.953
  comR Streptococcus thermophilus LMD-9

94.649

100

0.946
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.806

100

0.418

Multiple sequence alignment