Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NYE32_RS01285 Genome accession   NZ_CP150201
Coordinates   243951..246047 (+) Length   698 a.a.
NCBI ID   WP_037598988.1    Uniprot ID   A0A6N3AC06
Organism   Streptococcus sp. FSL R7-0248     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 238951..251047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS01260 (NYE32_01260) trkA 239041..240390 (-) 1350 WP_037598979.1 Trk system potassium transporter TrkA -
  NYE32_RS01265 (NYE32_01265) - 240668..241177 (+) 510 WP_002886541.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NYE32_RS01270 (NYE32_01270) - 241488..242045 (+) 558 WP_037598980.1 ECF transporter S component -
  NYE32_RS01275 (NYE32_01275) - 242048..242698 (+) 651 WP_037598982.1 phosphatase PAP2 family protein -
  NYE32_RS01280 (NYE32_01280) comR 242877..243776 (+) 900 WP_037598985.1 helix-turn-helix transcriptional regulator Regulator
  NYE32_RS01285 (NYE32_01285) comA 243951..246047 (+) 2097 WP_037598988.1 peptide cleavage/export ABC transporter Regulator
  NYE32_RS01290 (NYE32_01290) - 246158..246490 (+) 333 WP_002886546.1 DUF805 domain-containing protein -
  NYE32_RS01295 (NYE32_01295) - 246541..247932 (-) 1392 WP_037598995.1 DUF4153 domain-containing protein -
  NYE32_RS01300 (NYE32_01300) - 248339..248854 (+) 516 WP_002886548.1 AmiS/UreI family transporter -
  NYE32_RS01305 (NYE32_01305) - 248879..249181 (+) 303 WP_002886558.1 urease subunit gamma -
  NYE32_RS01310 (NYE32_01310) - 249193..249504 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 78350.34 Da        Isoelectric Point: 9.2047

>NTDB_id=966148 NYE32_RS01285 WP_037598988.1 243951..246047(+) (comA) [Streptococcus sp. FSL R7-0248]
MSKYPYISQVDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIVHVVKEGGLQHYYTVFGQIKGQLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGEAYTKYKEDVPGLLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQAIIDRLIPQGAYNLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALIVQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYREIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILCYGAQLVIEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEKGKLKELSFKQLAF
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGFEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILIFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=966148 NYE32_RS01285 WP_037598988.1 243951..246047(+) (comA) [Streptococcus sp. FSL R7-0248]
ATGTCAAAATATCCATATATTTCACAGGTTGATCAGCGTGATTGTGGTGTCGCTGCCTTGGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGAGAGTTGGCTCAGACTTCTCGTGAAGGTACTTCTGCGCTTGGTTTGGTGG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTATTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGTACATGTGGTTAAAGAAGGTGGGCTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGCAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAATTTGCCAAAGAGTGGACGGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAGCCTATACTAAATACAAAGAAGATGTACCTGGACTTCTTTCATTTTTACCAATTTTGTTT
CGTCGTAAGGGTTTGATTGCGGTTATTGTCTTATTAAGTTTTCTAGTGACCCTTGTTAATATTATTGGTTCTTATTATTT
GCAAGCTATTATCGACCGCTTGATTCCTCAGGGGGCCTATAATCTTCTGACCATGATTTCGCTAGGCTTATGTATCTCTT
ATCTTGCTCAACAAGTTTTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACCTGTCCATTGCTGTCATT
CTTCCTTATATCAAGCATGTCCTTTCCTTACCTATTAGTTTCTTTAGTTCACGTCGTACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACCATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTC
TAGCTGTGGCTCTTATTGTACAAAATCAGTCACTTTTTGTGATGACTCTCACAGTAGTTCCTCTTTATGTTTTAATCATT
CTGGCATTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGTATTGAAACCTTAAAATCCTTGAGGGTTGAGGAAAGACGCTATCGGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTCTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGCTATGGGGCACAATTGGTCATAGAAGGGCAACTATCTGCAGGTCAGTTGATTACCTATAATAT
GTTGTTGAATTATTTTACAACTCCTTTAATTAATATCATCAATCTCCAATCTAAAATTCAGCAAGCCAAAGTCGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGACAAGGAAGAAAAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTTTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACTCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGAAAAACGACCTTAGCTAAAATGTTGTCAGGTTATTATACGAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGTTGCGTCAAATGGTGACTTACGTTCCTCAGCAGACCTATGTG
TTTACGGGAACCATTTTAGAAAATCTGCTATTAGGATTTGAAGGAGAAGTTGACGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGCTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCAG
GTGGTCAAAAACAACGCTTGGCTATAGCGAGGGCTCTCTTGTCCAAACAGCCTATCTTGATTTTTGACGAAGCTACCAGT
GGTCTCGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTAGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(494-640)

ABC transporter transmembrane region (ABC_membrane)

(167-436)

Peptidase C39 family (Peptidase_C39)

(3-139)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N3AC06

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

53.401

98.997

0.529
  comA Streptococcus gordonii str. Challis substr. CH1

52.73

99.713

0.526
  comA Streptococcus mitis NCTC 12261

52.967

98.997

0.524
  comA Streptococcus pneumoniae Rx1

52.822

98.997

0.523
  comA Streptococcus pneumoniae D39

52.822

98.997

0.523
  comA Streptococcus pneumoniae R6

52.822

98.997

0.523
  comA Streptococcus pneumoniae TIGR4

52.677

98.997

0.521
  comA/nlmT Streptococcus mutans UA159

50.29

98.854

0.497

Multiple sequence alignment