Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NSQ79_RS01425 Genome accession   NZ_CP150200
Coordinates   264486..265385 (+) Length   299 a.a.
NCBI ID   WP_049529071.1    Uniprot ID   A0A6G4NCX0
Organism   Streptococcus sp. FSL W7-1342     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 259486..270385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NSQ79_RS01400 (NSQ79_01400) - 260803..261312 (+) 510 WP_049529100.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NSQ79_RS01405 (NSQ79_01405) - 261621..262178 (+) 558 WP_049529098.1 ECF transporter S component -
  NSQ79_RS01410 (NSQ79_01410) - 262181..262831 (+) 651 WP_045001950.1 phosphatase PAP2 family protein -
  NSQ79_RS01415 (NSQ79_01415) - 262945..263331 (-) 387 WP_002886743.1 IS110 family transposase -
  NSQ79_RS01420 (NSQ79_01420) - 263351..264112 (-) 762 WP_002886742.1 IS110 family transposase -
  NSQ79_RS01425 (NSQ79_01425) comR 264486..265385 (+) 900 WP_049529071.1 helix-turn-helix transcriptional regulator Regulator
  NSQ79_RS01430 (NSQ79_01430) comA 265560..267656 (+) 2097 WP_164332310.1 peptide cleavage/export ABC transporter Regulator
  NSQ79_RS01435 (NSQ79_01435) - 267767..268099 (+) 333 WP_014633880.1 DUF805 domain-containing protein -
  NSQ79_RS01440 (NSQ79_01440) - 268151..269542 (-) 1392 WP_014633611.1 DUF4153 domain-containing protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35174.66 Da        Isoelectric Point: 5.8054

>NTDB_id=966077 NSQ79_RS01425 WP_049529071.1 264486..265385(+) (comR) [Streptococcus sp. FSL W7-1342]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKNMADLLDHDNITIPDEYYE
MKNRLIKFPTYRNPERIKDKLALIEEVYEKFFELLPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKKKFST
NDLLVIDYYFFHLYGRKQYDKKLFEKIVKRVLNQEIWTDDVHNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QFYSYKPSVFVLKAKYELLHKGNKKKATENYDKAIMFASVLEDSVLEESIKAGKAADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=966077 NSQ79_RS01425 WP_049529071.1 264486..265385(+) (comR) [Streptococcus sp. FSL W7-1342]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGTCAGCAGATGTCACGTGAAGTACTATGTTT
AGATGGTGCGGAGTTGACTGTTCGCCAGTTAATTCGCATTGAAAAAGGGGAATCTCTCCCGTCTTTAGATAGACTATCTT
ACATCGCAAAACGTCTAGGAAAAAATATGGCCGATCTATTGGATCATGACAATATTACTATCCCTGATGAATATTATGAG
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCAGAAAGAATAAAGGATAAACTTGCCTTAATTGAGGAAGT
CTATGAGAAATTCTTTGAACTTCTTCCAGAAGAAGAACTATTAACTCTAGATATTTTGGAAAATATATTAAGTTTCACTA
GTTGGGAGGAGAGTCCAAAGGTTGAGGAAATATATGAAGATTTATTTGAACAGGTCAAAAGGAAGAAGAAATTCTCAACT
AACGATTTATTAGTTATTGACTATTATTTCTTCCATCTTTATGGAAGAAAACAGTATGACAAAAAACTTTTTGAAAAAAT
CGTAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTCCATAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTGAAGATTTTTCACAATTCCTTTTCAGACTTCTTAACAGTTGTGGATAAAGCATTAGCCGTTATAGAAAAATCA
CAATTCTATAGCTATAAACCTAGTGTTTTTGTTCTCAAAGCTAAATATGAACTTCTGCATAAGGGAAATAAGAAAAAGGC
TACAGAGAATTACGATAAGGCCATAATGTTTGCTTCCGTTTTAGAAGACTCGGTTTTAGAAGAAAGTATAAAAGCAGGGA
AAGCGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G4NCX0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

96.99

100

0.97
  comR Streptococcus salivarius SK126

96.321

100

0.963
  comR Streptococcus thermophilus LMG 18311

93.98

100

0.94
  comR Streptococcus thermophilus LMD-9

93.311

100

0.933
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421

Multiple sequence alignment