Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AABJ90_RS00390 Genome accession   NZ_AP028964
Coordinates   70113..71315 (+) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain NA05 = NBRC 116153     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 65113..76315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ90_RS00370 (BsubNA05_00700) walK 65194..67029 (+) 1836 WP_024572714.1 cell wall metabolism sensor histidine kinase WalK -
  AABJ90_RS00375 (BsubNA05_00710) walH 67019..68386 (+) 1368 WP_003226936.1 WalRK two-component regulatory system regulator WalH -
  AABJ90_RS00380 (BsubNA05_00720) walI 68373..69215 (+) 843 WP_046161072.1 WalRK two-component regulatory system regulator WalI -
  AABJ90_RS00385 (BsubNA05_00730) vicX 69237..70031 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  AABJ90_RS00390 (BsubNA05_00740) htrA 70113..71315 (+) 1203 WP_015250812.1 serine protease HtrC Regulator
  AABJ90_RS00395 - 71336..71462 (+) 127 Protein_74 hypothetical protein -
  AABJ90_RS00400 (BsubNA05_00750) - 71459..71959 (-) 501 WP_338382319.1 PepSY domain-containing protein -
  AABJ90_RS00405 (BsubNA05_00760) - 72120..73019 (-) 900 WP_338382320.1 PepSY domain-containing protein -
  AABJ90_RS00410 (BsubNA05_00770) - 73231..73914 (+) 684 WP_048654834.1 response regulator transcription factor -
  AABJ90_RS00415 (BsubNA05_00780) - 73911..75377 (+) 1467 WP_041337905.1 HAMP domain-containing sensor histidine kinase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=96567 AABJ90_RS00390 WP_015250812.1 70113..71315(+) (htrA) [Bacillus subtilis strain NA05 = NBRC 116153]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=96567 AABJ90_RS00390 WP_015250812.1 70113..71315(+) (htrA) [Bacillus subtilis strain NA05 = NBRC 116153]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGTAATGTGTCGCCCGCCGTTGTGGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATCGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATCCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378

Multiple sequence alignment