Detailed information NTG0962284

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR22_RS14100
• Genome accession: NZ_CP149937
• Coordinates: 2785296..2786183 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN124
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2780296..2791183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR22_RS14070 (UXR22_14070)	-	2780315..2780407 (+)	93	WP_010956583.1	hypothetical protein	-
UXR22_RS14075 (UXR22_14075)	-	2780515..2781012 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR22_RS14080 (UXR22_14080)	-	2781022..2781282 (-)	261	WP_001789910.1	hypothetical protein	-
UXR22_RS14085 (UXR22_14085)	-	2781664..2781777 (-)	114	WP_001791776.1	hypothetical protein	-
UXR22_RS14090 (UXR22_14090)	-	2782436..2784436 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR22_RS14095 (UXR22_14095)	-	2784433..2785188 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR22_RS14100 (UXR22_14100)	braS	2785296..2786183 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR22_RS14105 (UXR22_14105)	braR	2786194..2786859 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR22_RS14110 (UXR22_14110)	-	2786885..2787085 (-)	201	WP_000604728.1	hypothetical protein	-
UXR22_RS14115 (UXR22_14115)	-	2787283..2788707 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR22_RS14755	-	2788767..2788868 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR22_RS14125 (UXR22_14125)	-	2788990..2789445 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR22_RS14130 (UXR22_14130)	-	2789690..2790451 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=962284 UXR22_RS14100 WP_000143419.1 2785296..2786183(-) (braS) [Staphylococcus aureus strain BSN124]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=962284 UXR22_RS14100 WP_000143419.1 2785296..2786183(-) (braS) [Staphylococcus aureus strain BSN124]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997