Detailed information NTG0961509

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: V8N34_RS04180
• Genome accession: NZ_CP149804
• Coordinates: 865688..866359 (+)
• Length: 223 a.a.
• NCBI ID: WP_009909965.1
• Uniprot ID: A0A075SH40
• Organism: Streptococcus suis strain YA
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 860688..871359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V8N34_RS04150 (V8N34_04150)	pstC	860904..861821 (+)	918	WP_044681677.1	phosphate ABC transporter permease subunit PstC	-
V8N34_RS04155 (V8N34_04155)	pstA	861811..862698 (+)	888	WP_002937616.1	phosphate ABC transporter permease PstA	-
V8N34_RS04160 (V8N34_04160)	pstB	862723..863526 (+)	804	WP_002937615.1	phosphate ABC transporter ATP-binding protein PstB	-
V8N34_RS04165 (V8N34_04165)	pstB	863538..864296 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
V8N34_RS04170 (V8N34_04170)	phoU	864325..864981 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
V8N34_RS04175 (V8N34_04175)	-	865147..865494 (+)	348	WP_172078903.1	hypothetical protein	-
V8N34_RS04180 (V8N34_04180)	ciaR	865688..866359 (+)	672	WP_009909965.1	response regulator transcription factor	Regulator
V8N34_RS04185 (V8N34_04185)	ciaH	866352..867731 (+)	1380	WP_024381361.1	HAMP domain-containing sensor histidine kinase	Regulator
V8N34_RS04190 (V8N34_04190)	-	868055..869284 (+)	1230	WP_339059873.1	transglutaminase domain-containing protein	-
V8N34_RS04195 (V8N34_04195)	rpsT	869546..869794 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
V8N34_RS04200 (V8N34_04200)	coaA	869853..870773 (-)	921	WP_318825224.1	type I pantothenate kinase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25290.00 Da
• Isoelectric Point: 4.2183

>NTDB_id=961509 V8N34_RS04180 WP_009909965.1 865688..866359(+) (ciaR) [Streptococcus suis strain YA]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=961509 V8N34_RS04180 WP_009909965.1 865688..866359(+) (ciaR) [Streptococcus suis strain YA]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATTTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

3D structure

• AlphaFold DB: A0A075SH40

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363