Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V8N34_RS04185 Genome accession   NZ_CP149804
Coordinates   866352..867731 (+) Length   459 a.a.
NCBI ID   WP_024381361.1    Uniprot ID   A0A075SID2
Organism   Streptococcus suis strain YA     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 861352..872731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8N34_RS04155 (V8N34_04155) pstA 861811..862698 (+) 888 WP_002937616.1 phosphate ABC transporter permease PstA -
  V8N34_RS04160 (V8N34_04160) pstB 862723..863526 (+) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  V8N34_RS04165 (V8N34_04165) pstB 863538..864296 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  V8N34_RS04170 (V8N34_04170) phoU 864325..864981 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  V8N34_RS04175 (V8N34_04175) - 865147..865494 (+) 348 WP_172078903.1 hypothetical protein -
  V8N34_RS04180 (V8N34_04180) ciaR 865688..866359 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  V8N34_RS04185 (V8N34_04185) ciaH 866352..867731 (+) 1380 WP_024381361.1 HAMP domain-containing sensor histidine kinase Regulator
  V8N34_RS04190 (V8N34_04190) - 868055..869284 (+) 1230 WP_339059873.1 transglutaminase domain-containing protein -
  V8N34_RS04195 (V8N34_04195) rpsT 869546..869794 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  V8N34_RS04200 (V8N34_04200) coaA 869853..870773 (-) 921 WP_318825224.1 type I pantothenate kinase -
  V8N34_RS04205 (V8N34_04205) - 870882..871472 (+) 591 WP_024400689.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51961.70 Da        Isoelectric Point: 6.8882

>NTDB_id=961510 V8N34_RS04185 WP_024381361.1 866352..867731(+) (ciaH) [Streptococcus suis strain YA]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=961510 V8N34_RS04185 WP_024381361.1 866352..867731(+) (ciaH) [Streptococcus suis strain YA]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SID2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488