Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACF1RT_RS07220 Genome accession   NZ_CP172847
Coordinates   1447951..1448631 (-) Length   226 a.a.
NCBI ID   WP_226710905.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1442951..1453631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS07205 (ACF1RT_07205) holA 1443707..1444747 (-) 1041 WP_168752072.1 DNA polymerase III subunit delta -
  ACF1RT_RS07210 (ACF1RT_07210) - 1444915..1445541 (-) 627 WP_002264731.1 DUF805 domain-containing protein -
  ACF1RT_RS07215 (ACF1RT_07215) comEC/celB 1445727..1447961 (-) 2235 WP_226710906.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACF1RT_RS07220 (ACF1RT_07220) comEA/celA/cilE 1447951..1448631 (-) 681 WP_226710905.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACF1RT_RS07225 (ACF1RT_07225) - 1448771..1449523 (-) 753 WP_002264733.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ACF1RT_RS07230 (ACF1RT_07230) - 1449662..1450597 (+) 936 WP_019313136.1 polysaccharide deacetylase family protein -
  ACF1RT_RS07235 (ACF1RT_07235) - 1450686..1451198 (+) 513 WP_002261919.1 HXXEE domain-containing protein -
  ACF1RT_RS07240 (ACF1RT_07240) - 1451244..1452263 (+) 1020 WP_019313135.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24584.98 Da        Isoelectric Point: 8.2999

>NTDB_id=954439 ACF1RT_RS07220 WP_226710905.1 1447951..1448631(-) (comEA/celA/cilE) [Streptococcus mutans strain DPC6143]
MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRINDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETL
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=954439 ACF1RT_RS07220 WP_226710905.1 1447951..1448631(-) (comEA/celA/cilE) [Streptococcus mutans strain DPC6143]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCCCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAAACTGGCAAAGAAAGTCAAAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTAATGATGTGATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTTG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(163-223)

SLBB domain (SLBB)

(77-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.918

100

0.442
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae Rx1

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae D39

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae R6

42.06

100

0.434
  comEA/celA/cilE Streptococcus mitis SK321

41.202

100

0.425
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA Streptococcus thermophilus LMD-9

56.129

68.584

0.385
  comEA Latilactobacillus sakei subsp. sakei 23K

35.124

100

0.376