Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   QML92_RS05705 Genome accession   NZ_AP025937
Coordinates   1150994..1151644 (-) Length   216 a.a.
NCBI ID   WP_000387335.1    Uniprot ID   A0A0B7MF65
Organism   Streptococcus pneumoniae strain PZ900700792     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1145994..1156644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML92_RS05685 (PC0780_11270) - 1146599..1147780 (-) 1182 WP_000655958.1 ABC transporter permease -
  QML92_RS05690 (PC0780_11280) - 1147784..1148371 (-) 588 Protein_1132 ABC transporter ATP-binding protein -
  QML92_RS05695 (PC0780_11290) - 1148403..1148591 (-) 189 WP_010976492.1 hypothetical protein -
  QML92_RS05700 (PC0780_11300) comEC/celB 1148770..1151010 (-) 2241 WP_000942412.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QML92_RS05705 (PC0780_11310) comEA/celA/cilE 1150994..1151644 (-) 651 WP_000387335.1 helix-hairpin-helix domain-containing protein Machinery gene
  QML92_RS05710 (PC0780_11320) - 1151712..1152281 (-) 570 WP_000443774.1 GNAT family N-acetyltransferase -
  QML92_RS05715 ald 1152458..1153569 (+) 1112 Protein_1137 alanine dehydrogenase -
  QML92_RS05720 - 1153870..1154195 (-) 326 Protein_1138 TfoX/Sxy family protein -
  QML92_RS05725 (PC0780_11370) - 1154198..1154698 (-) 501 WP_000566982.1 GNAT family N-acetyltransferase -
  QML92_RS05730 (PC0780_11380) - 1154891..1155859 (-) 969 WP_000658183.1 PhoH family protein -
  QML92_RS05735 (PC0780_11390) - 1155945..1156160 (-) 216 WP_001232082.1 YozE family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23229.61 Da        Isoelectric Point: 5.2344

>NTDB_id=95277 QML92_RS05705 WP_000387335.1 1150994..1151644(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700792]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTNGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=95277 QML92_RS05705 WP_000387335.1 1150994..1151644(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900700792]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAATGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCT
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAATCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACTATAGAAAAGTTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MF65

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae D39

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae R6

99.074

100

0.991
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis NCTC 12261

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis SK321

90.278

100

0.903
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Bacillus subtilis subsp. subtilis str. 168

41.053

87.963

0.361

Multiple sequence alignment