Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U69_RS05545 Genome accession   NZ_CP145867
Coordinates   1228975..1229682 (-) Length   235 a.a.
NCBI ID   WP_037600497.1    Uniprot ID   A0AAW7PG55
Organism   Streptococcus salivarius strain KSS10     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1223975..1234682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS05520 (V6U69_05520) yidA 1224328..1225137 (+) 810 WP_002890845.1 sugar-phosphatase -
  V6U69_RS05525 (V6U69_05525) - 1225139..1226353 (+) 1215 WP_155198602.1 aminoacyltransferase -
  V6U69_RS05530 (V6U69_05530) - 1226405..1226764 (-) 360 WP_037597735.1 YbaN family protein -
  V6U69_RS05535 (V6U69_05535) vicX 1226824..1227636 (-) 813 WP_155198601.1 MBL fold metallo-hydrolase Regulator
  V6U69_RS05540 (V6U69_05540) vicK 1227642..1228982 (-) 1341 WP_410532015.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U69_RS05545 (V6U69_05545) vicR 1228975..1229682 (-) 708 WP_037600497.1 response regulator YycF Regulator
  V6U69_RS05550 (V6U69_05550) - 1229968..1230735 (+) 768 Protein_1078 amino acid ABC transporter ATP-binding protein -
  V6U69_RS05555 (V6U69_05555) - 1230745..1231578 (+) 834 WP_155198614.1 transporter substrate-binding domain-containing protein -
  V6U69_RS05560 (V6U69_05560) - 1231596..1232294 (+) 699 WP_084871397.1 amino acid ABC transporter permease -
  V6U69_RS05565 (V6U69_05565) - 1232306..1232956 (+) 651 WP_037601175.1 amino acid ABC transporter permease -
  V6U69_RS05570 (V6U69_05570) - 1233144..1233911 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27072.92 Da        Isoelectric Point: 4.8387

>NTDB_id=940788 V6U69_RS05545 WP_037600497.1 1228975..1229682(-) (vicR) [Streptococcus salivarius strain KSS10]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTNHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940788 V6U69_RS05545 WP_037600497.1 1228975..1229682(-) (vicR) [Streptococcus salivarius strain KSS10]
ATGAAAAAAATTCTTGTTGTTGATGATGAAAGACCAATTTCGGATATCATCAAGTTTAATCTGACTAAAGAAGGTTATGA
AGTAGTTACGGCCTTTGATGGTCGTGAAGCATTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGCTGCCTGAACTAGATGGTCTAGAAGTTGCTAAGGAAATTCGAAAGACAAATCATACACCAATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAACTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTAATGACGCGTGAACATTTGCTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGACA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.106

100

0.851
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.136

100

0.383