Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U69_RS05540 Genome accession   NZ_CP145867
Coordinates   1227642..1228982 (-) Length   446 a.a.
NCBI ID   WP_410532015.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1222642..1233982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS05515 (V6U69_05515) - 1223292..1224149 (-) 858 WP_173018075.1 GNAT family N-acetyltransferase -
  V6U69_RS05520 (V6U69_05520) yidA 1224328..1225137 (+) 810 WP_002890845.1 sugar-phosphatase -
  V6U69_RS05525 (V6U69_05525) - 1225139..1226353 (+) 1215 WP_155198602.1 aminoacyltransferase -
  V6U69_RS05530 (V6U69_05530) - 1226405..1226764 (-) 360 WP_037597735.1 YbaN family protein -
  V6U69_RS05535 (V6U69_05535) vicX 1226824..1227636 (-) 813 WP_155198601.1 MBL fold metallo-hydrolase Regulator
  V6U69_RS05540 (V6U69_05540) vicK 1227642..1228982 (-) 1341 WP_410532015.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U69_RS05545 (V6U69_05545) vicR 1228975..1229682 (-) 708 WP_037600497.1 response regulator YycF Regulator
  V6U69_RS05550 (V6U69_05550) - 1229968..1230735 (+) 768 Protein_1078 amino acid ABC transporter ATP-binding protein -
  V6U69_RS05555 (V6U69_05555) - 1230745..1231578 (+) 834 WP_155198614.1 transporter substrate-binding domain-containing protein -
  V6U69_RS05560 (V6U69_05560) - 1231596..1232294 (+) 699 WP_084871397.1 amino acid ABC transporter permease -
  V6U69_RS05565 (V6U69_05565) - 1232306..1232956 (+) 651 WP_037601175.1 amino acid ABC transporter permease -
  V6U69_RS05570 (V6U69_05570) - 1233144..1233911 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 51041.34 Da        Isoelectric Point: 5.1660

>NTDB_id=940787 V6U69_RS05540 WP_410532015.1 1227642..1228982(-) (vicK) [Streptococcus salivarius strain KSS10]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETAKQMSILDLLDGENPYTYNELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTDKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=940787 V6U69_RS05540 WP_410532015.1 1227642..1228982(-) (vicK) [Streptococcus salivarius strain KSS10]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTCAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTT
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTATATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
AACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAATGAATTGTTATCTAAGACTCCTGAGATT
CATTTGTCTCGTCGAGATGCCAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCCCTTATTCGTAAAGAATCTGGTTT
TATCTCAGGTCTGGTTGCCGTCCTTCACGATGCTACTGAGCAGGAAAAAGAAGAGCGGGAACGCCGACTCTTTGTATCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCTTATCTGGAGGCACTTGATGATGGTGCTCTTGACGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAGCTTGACGTTGAAATGACTAATTTCACGGCCTTCATGACCTATATATTGAATC
GTTTCGATCAGATTAAGAGTCAAGAAACCAATACAGATAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCGATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATCCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGTATTCCTA
AGAAGGATTTGCCGTTAATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657