Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U68_RS04675 Genome accession   NZ_CP145866
Coordinates   946343..947050 (+) Length   235 a.a.
NCBI ID   WP_037600497.1    Uniprot ID   A0AAW7PG55
Organism   Streptococcus salivarius strain KSS9     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 941343..952050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS04650 (V6U68_04640) - 942114..942881 (-) 768 WP_037601338.1 amino acid ABC transporter ATP-binding protein -
  V6U68_RS04655 (V6U68_04645) - 943069..943719 (-) 651 WP_037601175.1 amino acid ABC transporter permease -
  V6U68_RS04660 (V6U68_04650) - 943731..944429 (-) 699 WP_347093264.1 amino acid ABC transporter permease -
  V6U68_RS04665 (V6U68_04655) - 944447..945280 (-) 834 WP_410532014.1 transporter substrate-binding domain-containing protein -
  V6U68_RS04670 (V6U68_04660) - 945290..946057 (-) 768 WP_301354528.1 amino acid ABC transporter ATP-binding protein -
  V6U68_RS04675 (V6U68_04665) vicR 946343..947050 (+) 708 WP_037600497.1 response regulator YycF Regulator
  V6U68_RS04680 (V6U68_04670) vicK 947043..948383 (+) 1341 WP_410532015.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U68_RS04685 (V6U68_04675) vicX 948389..949201 (+) 813 WP_155198601.1 MBL fold metallo-hydrolase Regulator
  V6U68_RS04690 (V6U68_04680) - 949261..949620 (+) 360 WP_410532016.1 YbaN family protein -
  V6U68_RS04695 (V6U68_04685) - 949672..950886 (-) 1215 WP_410532017.1 aminoacyltransferase -
  V6U68_RS04700 (V6U68_04690) yidA 950888..951697 (-) 810 WP_002890845.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27072.92 Da        Isoelectric Point: 4.8387

>NTDB_id=940715 V6U68_RS04675 WP_037600497.1 946343..947050(+) (vicR) [Streptococcus salivarius strain KSS9]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTNHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940715 V6U68_RS04675 WP_037600497.1 946343..947050(+) (vicR) [Streptococcus salivarius strain KSS9]
ATGAAAAAAATTCTTGTTGTTGATGATGAAAGACCAATTTCGGATATCATCAAGTTTAATCTGACTAAAGAAGGTTATGA
AGTAGTTACGGCCTTTGATGGTCGTGAAGCATTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTGGACTTGA
TGCTGCCTGAACTAGATGGTCTAGAAGTTGCTAAGGAAATTCGAAAGACAAATCATACACCAATTATCATGCTTTCAGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCAGATGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCAGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAACTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTAATGACGCGTGAACATTTGCTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGACA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.106

100

0.851
  micA Streptococcus pneumoniae Cp1015

80.258

99.149

0.796
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.136

100

0.383