Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U68_RS04680 Genome accession   NZ_CP145866
Coordinates   947043..948383 (+) Length   446 a.a.
NCBI ID   WP_410532015.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 942043..953383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS04650 (V6U68_04640) - 942114..942881 (-) 768 WP_037601338.1 amino acid ABC transporter ATP-binding protein -
  V6U68_RS04655 (V6U68_04645) - 943069..943719 (-) 651 WP_037601175.1 amino acid ABC transporter permease -
  V6U68_RS04660 (V6U68_04650) - 943731..944429 (-) 699 WP_347093264.1 amino acid ABC transporter permease -
  V6U68_RS04665 (V6U68_04655) - 944447..945280 (-) 834 WP_410532014.1 transporter substrate-binding domain-containing protein -
  V6U68_RS04670 (V6U68_04660) - 945290..946057 (-) 768 WP_301354528.1 amino acid ABC transporter ATP-binding protein -
  V6U68_RS04675 (V6U68_04665) vicR 946343..947050 (+) 708 WP_037600497.1 response regulator YycF Regulator
  V6U68_RS04680 (V6U68_04670) vicK 947043..948383 (+) 1341 WP_410532015.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U68_RS04685 (V6U68_04675) vicX 948389..949201 (+) 813 WP_155198601.1 MBL fold metallo-hydrolase Regulator
  V6U68_RS04690 (V6U68_04680) - 949261..949620 (+) 360 WP_410532016.1 YbaN family protein -
  V6U68_RS04695 (V6U68_04685) - 949672..950886 (-) 1215 WP_410532017.1 aminoacyltransferase -
  V6U68_RS04700 (V6U68_04690) yidA 950888..951697 (-) 810 WP_002890845.1 sugar-phosphatase -
  V6U68_RS04705 (V6U68_04695) - 951876..952742 (+) 867 WP_410532018.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 51041.34 Da        Isoelectric Point: 5.1660

>NTDB_id=940716 V6U68_RS04680 WP_410532015.1 947043..948383(+) (vicK) [Streptococcus salivarius strain KSS9]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETAKQMSILDLLDGENPYTYNELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTDKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=940716 V6U68_RS04680 WP_410532015.1 947043..948383(+) (vicK) [Streptococcus salivarius strain KSS9]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTTTTTGTGGCTTTCTACTTTAT
TTTTCTTGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGAGTAAAGTCCCTAATGGCAGGTA
ACTATAATGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTT
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTATATGAGTGATGGAGTCAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAAACAGCGA
AACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAATGAATTGTTATCTAAGACTCCTGAGATT
CATTTGTCTCGTCGAGATGCCAACGATGAGTTTGTGACCCTACGCGTTAACTTTGCCCTTATTCGTAAAGAATCTGGTTT
TATCTCAGGTCTGGTTGCCGTCCTTCACGATGCTACTGAGCAGGAAAAAGAAGAGCGGGAACGCCGACTCTTTGTATCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCTTATCTGGAGGCACTTGATGATGGTGCTCTTGACGAA
GAGATTGCCCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAGCTTGACGTTGAAATGACTAATTTCACGGCCTTCATGACCTATATATTGAATC
GTTTCGATCAGATTAAGAGTCAAGAAACCAATACAGATAAAACTTACGAAATTATTCGAGATTATCCGGTAAACTCGATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATCCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGTATTCCTA
AGAAGGATTTGCCGTTAATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACTGGTCTT
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657