Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   V6U67_RS09750 Genome accession   NZ_CP145865
Coordinates   2086921..2087109 (-) Length   62 a.a.
NCBI ID   WP_410531180.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS8     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2065504..2093640 2086921..2087109 within 0


Gene organization within MGE regions


Location: 2065504..2093640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS09630 (V6U67_09630) - 2065504..2065758 (-) 255 WP_129852295.1 hypothetical protein -
  V6U67_RS09635 (V6U67_09635) - 2065818..2066166 (-) 349 Protein_1839 diacylglycerol kinase family lipid kinase -
  V6U67_RS09640 (V6U67_09640) - 2066168..2066311 (-) 144 Protein_1840 IS982 family transposase -
  V6U67_RS09645 (V6U67_09645) - 2066663..2067271 (+) 609 WP_129852297.1 DUF1269 domain-containing protein -
  V6U67_RS09650 (V6U67_09650) - 2067513..2067683 (+) 171 Protein_1842 tyrosine-type recombinase/integrase -
  V6U67_RS09655 (V6U67_09655) - 2068306..2069502 (+) 1197 Protein_1843 tyrosine-type recombinase/integrase -
  V6U67_RS09660 (V6U67_09660) - 2069937..2071391 (+) 1455 Protein_1844 IS1182 family transposase -
  V6U67_RS09665 (V6U67_09665) - 2072221..2072648 (+) 428 Protein_1845 UDP-N-acetylglucosamine 2-epimerase -
  V6U67_RS09670 (V6U67_09670) - 2072622..2073004 (+) 383 Protein_1846 UDP-N-acetylglucosamine 2-epimerase -
  V6U67_RS09675 (V6U67_09675) - 2073034..2073267 (+) 234 Protein_1847 PfkB family carbohydrate kinase -
  V6U67_RS09680 (V6U67_09680) - 2073289..2074323 (+) 1035 WP_022496166.1 GGDEF domain-containing protein -
  V6U67_RS09685 (V6U67_09685) - 2074320..2075384 (+) 1065 WP_037601258.1 bifunctional glycosyltransferase family 2/GtrA family protein -
  V6U67_RS09690 (V6U67_09690) - 2075374..2077599 (+) 2226 WP_022496165.1 glycosyltransferase family 2 protein -
  V6U67_RS09695 (V6U67_09695) - 2077596..2079536 (+) 1941 WP_022496164.1 hypothetical protein -
  V6U67_RS09700 (V6U67_09700) - 2079649..2079840 (-) 192 Protein_1852 DNA polymerase -
  V6U67_RS09705 (V6U67_09705) - 2080168..2080788 (+) 621 WP_022496163.1 hypothetical protein -
  V6U67_RS09710 (V6U67_09710) - 2080821..2081099 (+) 279 WP_022496162.1 hypothetical protein -
  V6U67_RS09715 (V6U67_09715) - 2081101..2081892 (+) 792 WP_022496161.1 hypothetical protein -
  V6U67_RS09720 (V6U67_09720) - 2081867..2082367 (+) 501 WP_022496160.1 hypothetical protein -
  V6U67_RS09725 (V6U67_09725) - 2082597..2082686 (-) 90 Protein_1857 CoA pyrophosphatase -
  V6U67_RS09730 (V6U67_09730) - 2082743..2085112 (-) 2370 WP_022496155.1 YhgE/Pip domain-containing protein -
  V6U67_RS09735 (V6U67_09735) - 2085241..2085780 (+) 540 WP_002885702.1 TetR/AcrR family transcriptional regulator -
  V6U67_RS09740 (V6U67_09740) - 2085857..2086219 (-) 363 WP_022496154.1 DUF1304 domain-containing protein -
  V6U67_RS09745 (V6U67_09745) - 2086335..2086523 (+) 189 WP_002885644.1 hypothetical protein -
  V6U67_RS09750 (V6U67_09750) prx 2086921..2087109 (-) 189 WP_410531180.1 hypothetical protein Regulator
  V6U67_RS09755 (V6U67_09755) - 2087385..2087822 (-) 438 WP_410531181.1 hypothetical protein -
  V6U67_RS09760 (V6U67_09760) - 2088055..2088318 (-) 264 WP_410531182.1 hypothetical protein -
  V6U67_RS09765 (V6U67_09765) - 2088315..2088512 (-) 198 WP_410531183.1 DUF2758 domain-containing protein -
  V6U67_RS09770 (V6U67_09770) - 2088838..2090250 (-) 1413 WP_410531303.1 VapE domain-containing protein -
  V6U67_RS09775 (V6U67_09775) - 2090247..2091104 (-) 858 WP_410531184.1 primase alpha helix C-terminal domain-containing protein -
  V6U67_RS09780 (V6U67_09780) - 2091121..2091393 (-) 273 WP_195320566.1 MerR family transcriptional regulator -
  V6U67_RS09785 (V6U67_09785) - 2091380..2091736 (-) 357 WP_410531185.1 hypothetical protein -
  V6U67_RS09790 (V6U67_09790) - 2091723..2091968 (-) 246 WP_410531186.1 hypothetical protein -
  V6U67_RS09795 (V6U67_09795) - 2091982..2092188 (-) 207 WP_410531187.1 hypothetical protein -
  V6U67_RS09800 (V6U67_09800) - 2092192..2092494 (-) 303 WP_347093488.1 hypothetical protein -
  V6U67_RS09805 (V6U67_09805) - 2092720..2092917 (-) 198 WP_183139963.1 helix-turn-helix transcriptional regulator -
  V6U67_RS09810 (V6U67_09810) - 2093074..2093640 (+) 567 WP_410531188.1 helix-turn-helix transcriptional regulator -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7113.94 Da        Isoelectric Point: 4.3304

>NTDB_id=940681 V6U67_RS09750 WP_410531180.1 2086921..2087109(-) (prx) [Streptococcus salivarius strain KSS8]
MLTYDEFKEAMDNGFIKGDTVQIVRKNGKIHDYVLDGERVESHETLSLEKVSDIIKELGEDN

Nucleotide


Download         Length: 189 bp        

>NTDB_id=940681 V6U67_RS09750 WP_410531180.1 2086921..2087109(-) (prx) [Streptococcus salivarius strain KSS8]
ATGCTAACCTATGATGAATTTAAAGAGGCTATGGACAATGGTTTTATTAAAGGTGATACTGTCCAGATAGTCCGAAAGAA
CGGTAAGATCCATGACTACGTTTTAGACGGTGAACGAGTTGAGTCACACGAAACATTGAGTTTAGAAAAGGTATCGGATA
TAATAAAGGAACTAGGCGAGGACAACTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

60.345

93.548

0.565

  prx Streptococcus pyogenes MGAS315

60.345

93.548

0.565

  prx Streptococcus pyogenes MGAS315

56.897

93.548

0.532

  prx Streptococcus pyogenes MGAS315

55.932

95.161

0.532

  prx Streptococcus pyogenes MGAS315

73.81

67.742

0.5

  prx Streptococcus pyogenes MGAS315

70.732

66.129

0.468

  prx Streptococcus pyogenes MGAS315

66.667

67.742

0.452