Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U67_RS04625 Genome accession   NZ_CP145865
Coordinates   944954..945661 (+) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain KSS8     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 939954..950661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS04600 (V6U67_04600) - 940710..941477 (-) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -
  V6U67_RS04605 (V6U67_04605) - 941666..942316 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U67_RS04610 (V6U67_04610) - 942328..943026 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U67_RS04615 (V6U67_04615) - 943044..943877 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  V6U67_RS04620 (V6U67_04620) - 943887..944654 (-) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -
  V6U67_RS04625 (V6U67_04625) vicR 944954..945661 (+) 708 WP_002884978.1 response regulator YycF Regulator
  V6U67_RS04630 (V6U67_04630) vicK 945654..946994 (+) 1341 WP_022496319.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U67_RS04635 (V6U67_04635) vicX 947000..947812 (+) 813 WP_022496320.1 MBL fold metallo-hydrolase Regulator
  V6U67_RS04640 (V6U67_04640) - 947871..948230 (+) 360 WP_037611660.1 YbaN family protein -
  V6U67_RS04645 (V6U67_04645) - 948282..949496 (-) 1215 WP_037611659.1 aminoacyltransferase -
  V6U67_RS04650 (V6U67_04650) yidA 949498..950307 (-) 810 WP_002890845.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=940645 V6U67_RS04625 WP_002884978.1 944954..945661(+) (vicR) [Streptococcus salivarius strain KSS8]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940645 V6U67_RS04625 WP_002884978.1 944954..945661(+) (vicR) [Streptococcus salivarius strain KSS8]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCGGATATCATCAAGTTTAACCTGACTAAAGAGGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAACCAGACTTGGTCATCCTAGACTTGA
TGTTGCCTGAACTAGATGGCTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCAATTATCATGCTTTCCGCT
AAGGATAGCGAGTTCGATAAGGTTATAGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387