Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U67_RS04630 Genome accession   NZ_CP145865
Coordinates   945654..946994 (+) Length   446 a.a.
NCBI ID   WP_022496319.1    Uniprot ID   A0AB33ZD42
Organism   Streptococcus salivarius strain KSS8     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 940654..951994
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U67_RS04600 (V6U67_04600) - 940710..941477 (-) 768 WP_151405000.1 amino acid ABC transporter ATP-binding protein -
  V6U67_RS04605 (V6U67_04605) - 941666..942316 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U67_RS04610 (V6U67_04610) - 942328..943026 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U67_RS04615 (V6U67_04615) - 943044..943877 (-) 834 WP_037611665.1 transporter substrate-binding domain-containing protein -
  V6U67_RS04620 (V6U67_04620) - 943887..944654 (-) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -
  V6U67_RS04625 (V6U67_04625) vicR 944954..945661 (+) 708 WP_002884978.1 response regulator YycF Regulator
  V6U67_RS04630 (V6U67_04630) vicK 945654..946994 (+) 1341 WP_022496319.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U67_RS04635 (V6U67_04635) vicX 947000..947812 (+) 813 WP_022496320.1 MBL fold metallo-hydrolase Regulator
  V6U67_RS04640 (V6U67_04640) - 947871..948230 (+) 360 WP_037611660.1 YbaN family protein -
  V6U67_RS04645 (V6U67_04645) - 948282..949496 (-) 1215 WP_037611659.1 aminoacyltransferase -
  V6U67_RS04650 (V6U67_04650) yidA 949498..950307 (-) 810 WP_002890845.1 sugar-phosphatase -
  V6U67_RS04655 (V6U67_04655) - 950485..951351 (+) 867 WP_022495838.1 GNAT family N-acetyltransferase -
  V6U67_RS04660 (V6U67_04660) - 951433..951819 (+) 387 WP_002890847.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50885.17 Da        Isoelectric Point: 5.1606

>NTDB_id=940646 V6U67_RS04630 WP_022496319.1 945654..946994(+) (vicK) [Streptococcus salivarius strain KSS8]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPCDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=940646 V6U67_RS04630 WP_022496319.1 945654..946994(+) (vicK) [Streptococcus salivarius strain KSS8]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTTAT
TGCGACAAATCGCCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGATCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGATGTTGAGATGACTAATTTCACAGCCTTCATGACCTATATCTTGAATC
GTTTTGACCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGAGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACTCAGGTCGTGGATAATATTCTTAACAATGCCATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGACTCACAGTTAATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCAAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCCATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATGTGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.43

92.825

0.682
  micB Streptococcus pneumoniae Cp1015

67.436

97.085

0.655