Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   V6U64_RS05490 Genome accession   NZ_CP145862
Coordinates   1224973..1225680 (-) Length   235 a.a.
NCBI ID   WP_002884978.1    Uniprot ID   A0AB33ZBK5
Organism   Streptococcus salivarius strain KSS4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1219973..1230680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS05465 (V6U64_05460) yidA 1220327..1221136 (+) 810 WP_002890845.1 sugar-phosphatase -
  V6U64_RS05470 (V6U64_05465) - 1221138..1222352 (+) 1215 WP_073687783.1 aminoacyltransferase -
  V6U64_RS05475 (V6U64_05470) - 1222404..1222763 (-) 360 WP_037611660.1 YbaN family protein -
  V6U64_RS05480 (V6U64_05475) vicX 1222822..1223631 (-) 810 WP_126405093.1 MBL fold metallo-hydrolase Regulator
  V6U64_RS05485 (V6U64_05480) vicK 1223637..1224980 (-) 1344 WP_410536163.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U64_RS05490 (V6U64_05485) vicR 1224973..1225680 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V6U64_RS05495 (V6U64_05490) - 1225965..1226732 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6U64_RS05500 (V6U64_05495) - 1226742..1227575 (+) 834 WP_410539637.1 transporter substrate-binding domain-containing protein -
  V6U64_RS05505 (V6U64_05500) - 1227593..1228291 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U64_RS05510 (V6U64_05505) - 1228303..1228953 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U64_RS05515 (V6U64_05510) - 1229141..1229908 (+) 768 WP_037604317.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27045.90 Da        Isoelectric Point: 4.8387

>NTDB_id=940450 V6U64_RS05490 WP_002884978.1 1224973..1225680(-) (vicR) [Streptococcus salivarius strain KSS4]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=940450 V6U64_RS05490 WP_002884978.1 1224973..1225680(-) (vicR) [Streptococcus salivarius strain KSS4]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCGATTTCGGATATCATCAAGTTTAATCTAACTAAAGAAGGTTATGA
AGTGGTTACAGCCTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCACACACCGATTATCATGCTTTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGGCTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACTTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTCGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATCTGGCAACTCACATGGGACAAGTGATGACGCGTGAGCATTTACTTGAAAC
TGTTTGGGGTTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

85.532

100

0.855
  micA Streptococcus pneumoniae Cp1015

80.687

99.149

0.8
  covR Streptococcus salivarius strain HSISS4

44.872

99.574

0.447
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  scnR Streptococcus mutans UA159

38.559

100

0.387