Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U64_RS05485 Genome accession   NZ_CP145862
Coordinates   1223637..1224980 (-) Length   447 a.a.
NCBI ID   WP_410536163.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1218637..1229980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS05455 (V6U64_05450) - 1218814..1219200 (-) 387 WP_048790817.1 DUF1934 domain-containing protein -
  V6U64_RS05460 (V6U64_05455) - 1219283..1220149 (-) 867 WP_288587243.1 GNAT family N-acetyltransferase -
  V6U64_RS05465 (V6U64_05460) yidA 1220327..1221136 (+) 810 WP_002890845.1 sugar-phosphatase -
  V6U64_RS05470 (V6U64_05465) - 1221138..1222352 (+) 1215 WP_073687783.1 aminoacyltransferase -
  V6U64_RS05475 (V6U64_05470) - 1222404..1222763 (-) 360 WP_037611660.1 YbaN family protein -
  V6U64_RS05480 (V6U64_05475) vicX 1222822..1223631 (-) 810 WP_126405093.1 MBL fold metallo-hydrolase Regulator
  V6U64_RS05485 (V6U64_05480) vicK 1223637..1224980 (-) 1344 WP_410536163.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U64_RS05490 (V6U64_05485) vicR 1224973..1225680 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V6U64_RS05495 (V6U64_05490) - 1225965..1226732 (+) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  V6U64_RS05500 (V6U64_05495) - 1226742..1227575 (+) 834 WP_410539637.1 transporter substrate-binding domain-containing protein -
  V6U64_RS05505 (V6U64_05500) - 1227593..1228291 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U64_RS05510 (V6U64_05505) - 1228303..1228953 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U64_RS05515 (V6U64_05510) - 1229141..1229908 (+) 768 WP_037604317.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 51061.24 Da        Isoelectric Point: 4.9286

>NTDB_id=940449 V6U64_RS05485 WP_410536163.1 1223637..1224980(-) (vicK) [Streptococcus salivarius strain KSS4]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQESNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGEITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEME

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=940449 V6U64_RS05485 WP_410536163.1 1223637..1224980(-) (vicK) [Streptococcus salivarius strain KSS4]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGAGTTAT
TGCGACAAATCGCCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAAGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGATCTCTTGGCACT
GTCACGTATTGACAATAAGAGTACCCAACTTGATGTTGAGATGACTAATTTCACAGCCTTCATGACCTATATCTTGAATC
GTTTTGACCAGATTAAAAGTCAAGAAAGCAATACTGGTAAGACGTACGAAATTATTCGAGATTACCCTGTAAATTCTATT
TGGGTGGAGATTGATACGGATAAGATGACTCAGGTCGTGGATAATATTCTTAACAATGCCATCAAGTATTCTCCTGATGG
TGGTGAGATTACAGTGTCCATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGTATCCCTA
AGAAAGATTTACCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAGGGTGGAACGGGTCTA
GGCTTGTCCATTGCCAAAGAGATTATTAAACAACATAAGGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
ATTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGGAGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.617

0.682
  micB Streptococcus pneumoniae Cp1015

67.436

96.868

0.653