Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   V6U64_RS02370 Genome accession   NZ_CP145862
Coordinates   451722..452417 (+) Length   231 a.a.
NCBI ID   WP_022496133.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS4     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 446722..457417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS02345 (V6U64_02345) - 447064..448650 (+) 1587 WP_410536887.1 DEAD/DEAH box helicase -
  V6U64_RS02350 (V6U64_02350) - 448706..448975 (-) 270 WP_022496129.1 GIY-YIG nuclease family protein -
  V6U64_RS02355 (V6U64_02355) - 448979..449743 (-) 765 WP_022496130.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  V6U64_RS02360 (V6U64_02360) - 449793..450728 (-) 936 WP_049545587.1 polysaccharide deacetylase family protein -
  V6U64_RS02365 (V6U64_02365) - 450858..451613 (+) 756 WP_022496132.1 lysophospholipid acyltransferase family protein -
  V6U64_RS02370 (V6U64_02370) comEA 451722..452417 (+) 696 WP_022496133.1 helix-hairpin-helix domain-containing protein Machinery gene
  V6U64_RS02375 (V6U64_02375) comEC/celB 452407..454647 (+) 2241 WP_349955294.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V6U64_RS02380 (V6U64_02380) - 454733..455995 (+) 1263 WP_084915391.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  V6U64_RS02385 (V6U64_02385) - 456061..456606 (+) 546 WP_013991031.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24362.26 Da        Isoelectric Point: 4.7321

>NTDB_id=940433 V6U64_RS02370 WP_022496133.1 451722..452417(+) (comEA) [Streptococcus salivarius strain KSS4]
MKEKIIAYVKDNRLFVSVIALLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKDK
SKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVVYVATKDENLSVLGQSGTGQVSDKG
GQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSVDDLKNVSGIGDKTLEKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=940433 V6U64_RS02370 WP_022496133.1 451722..452417(+) (comEA) [Streptococcus salivarius strain KSS4]
GTGAAGGAAAAGATTATAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTTTACTGATGGTGATTTTTTG
CTTCTTTCTATGGATGACTTGTGGTGCGGGCAACAGTATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCATCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGATAAG
TCAAAAGTAACAGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTAACTGA
TGCCATCAAAGCCGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAACTTAGCTGCAAGCCTGTCGGACGAAG
AGGTTGTCTATGTGGCAACTAAGGATGAAAACCTTTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTTTCTGACAAAGGA
GGGCAAACTAGTGCTAAGGATGGCAAAATTAACTTAAACACAGCGACTTCAGAGGAGTTGCAAACTATTTCTGGGATTGG
AGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGAGGTTTTCAATCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACTTTAGAAAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(168-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

91.775

100

0.918
  comEA/celA/cilE Streptococcus mitis SK321

42.358

99.134

0.42
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.228

98.701

0.407
  comEA/celA/cilE Streptococcus mitis NCTC 12261

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae Rx1

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

40.789

98.701

0.403
  comEA/celA/cilE Streptococcus pneumoniae R6

40.789

98.701

0.403