Detailed information NTG0940434

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U64_RS02375
• Genome accession: NZ_CP145862
• Coordinates: 452407..454647 (+)
• Length: 746 a.a.
• NCBI ID: WP_349955294.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 447407..459647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U64_RS02350 (V6U64_02350)	-	448706..448975 (-)	270	WP_022496129.1	GIY-YIG nuclease family protein	-
V6U64_RS02355 (V6U64_02355)	-	448979..449743 (-)	765	WP_022496130.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U64_RS02360 (V6U64_02360)	-	449793..450728 (-)	936	WP_049545587.1	polysaccharide deacetylase family protein	-
V6U64_RS02365 (V6U64_02365)	-	450858..451613 (+)	756	WP_022496132.1	lysophospholipid acyltransferase family protein	-
V6U64_RS02370 (V6U64_02370)	comEA	451722..452417 (+)	696	WP_022496133.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U64_RS02375 (V6U64_02375)	comEC/celB	452407..454647 (+)	2241	WP_349955294.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U64_RS02380 (V6U64_02380)	-	454733..455995 (+)	1263	WP_084915391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U64_RS02385 (V6U64_02385)	-	456061..456606 (+)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
V6U64_RS02390 (V6U64_02390)	spxR	456599..457879 (+)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U64_RS02395 (V6U64_02395)	-	457924..458784 (+)	861	WP_004183173.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84435.27 Da
• Isoelectric Point: 9.9046

>NTDB_id=940434 V6U64_RS02375 WP_349955294.1 452407..454647(+) (comEC/celB) [Streptococcus salivarius strain KSS4]
MWLKKAPINLFSLALLIAALYFTIFNTNVYATGVLSFLLGCFLKHHWKNKVALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APTEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSLAIGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLGKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTFYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940434 V6U64_RS02375 WP_349955294.1 452407..454647(+) (comEC/celB) [Streptococcus salivarius strain KSS4]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTAACAC
AAATGTTTATGCTACTGGGGTTTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGTAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGTTGGTATTAAAAGGGAAAATAAAGTTATCCCTAGCAATTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAACGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGGTAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGATTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTGTGTTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACTTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTTCTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTCTTCTTTGCTCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTCTTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae R6	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.514	99.196	0.432