Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LLL8_RS07770 Genome accession   NZ_AP025700
Coordinates   1606707..1607399 (-) Length   230 a.a.
NCBI ID   WP_251899733.1    Uniprot ID   -
Organism   Lactococcus lactis strain L8     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1601707..1612399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLL8_RS07755 (LLL8_15190) - 1603326..1603667 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  LLL8_RS07760 (LLL8_15200) - 1603799..1605040 (-) 1242 WP_012898207.1 ammonium transporter -
  LLL8_RS07765 (LLL8_15210) covS 1605223..1606698 (-) 1476 WP_010906048.1 HAMP domain-containing histidine kinase Regulator
  LLL8_RS07770 (LLL8_15220) covR 1606707..1607399 (-) 693 WP_251899733.1 response regulator transcription factor Regulator
  LLL8_RS07775 (LLL8_15230) - 1607555..1608085 (-) 531 WP_058203054.1 DUF177 domain-containing protein -
  LLL8_RS07780 (LLL8_15240) - 1608216..1608461 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  LLL8_RS07785 (LLL8_15250) - 1608617..1609081 (-) 465 WP_029344120.1 hypothetical protein -
  LLL8_RS07790 (LLL8_15260) - 1609163..1609525 (-) 363 WP_010906050.1 TIGR02328 family protein -
  LLL8_RS07795 (LLL8_15270) - 1609751..1610662 (-) 912 WP_058223280.1 CHAP domain-containing protein -
  LLL8_RS07800 (LLL8_15280) - 1610775..1611611 (-) 837 WP_139917167.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26714.39 Da        Isoelectric Point: 5.1273

>NTDB_id=93692 LLL8_RS07770 WP_251899733.1 1606707..1607399(-) (covR) [Lactococcus lactis strain L8]
MTSKKILIIEDEKNLARFVSLELEHEGYTTEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=93692 LLL8_RS07770 WP_251899733.1 1606707..1607399(-) (covR) [Lactococcus lactis strain L8]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATACGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.565

100

0.996
  covR Streptococcus salivarius strain HSISS4

68.421

99.13

0.678
  vicR Streptococcus mutans UA159

45.887

100

0.461
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.611

98.261

0.37
  ciaR Streptococcus pneumoniae Rx1

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae D39

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae R6

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae TIGR4

36.726

98.261

0.361

Multiple sequence alignment