Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   ACD268_RS10690 Genome accession   NZ_CP168299
Coordinates   2047726..2048166 (-) Length   146 a.a.
NCBI ID   WP_001206585.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2042726..2053166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS10660 (ACD268_10660) - 2043035..2043910 (+) 876 WP_050103846.1 substrate-binding domain-containing protein -
  ACD268_RS10665 (ACD268_10665) pstC 2044028..2044891 (+) 864 WP_000595182.1 phosphate ABC transporter permease subunit PstC -
  ACD268_RS10670 (ACD268_10670) pstA 2044884..2045699 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  ACD268_RS10675 (ACD268_10675) pstB 2045701..2046453 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  ACD268_RS10680 (ACD268_10680) phoU 2046468..2047118 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  ACD268_RS10685 (ACD268_10685) - 2047159..2047611 (+) 453 Protein_2065 transposase -
  ACD268_RS10690 (ACD268_10690) comR 2047726..2048166 (-) 441 WP_001206585.1 helix-turn-helix transcriptional regulator Regulator
  ACD268_RS10695 (ACD268_10695) - 2048378..2049394 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ACD268_RS10700 (ACD268_10700) galU 2049416..2050315 (+) 900 WP_000202229.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  ACD268_RS10705 (ACD268_10705) - 2050382..2051059 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  ACD268_RS10710 (ACD268_10710) - 2051043..2051582 (-) 540 WP_000834309.1 5-formyltetrahydrofolate cyclo-ligase -
  ACD268_RS10715 (ACD268_10715) - 2051594..2052724 (-) 1131 WP_000886121.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17600.33 Da        Isoelectric Point: 5.1703

>NTDB_id=935484 ACD268_RS10690 WP_001206585.1 2047726..2048166(-) (comR) [Streptococcus pneumoniae strain FC1]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFAKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=935484 ACD268_RS10690 WP_001206585.1 2047726..2048166(-) (comR) [Streptococcus pneumoniae strain FC1]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGTTGAGGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGCTAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(8-59)

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.167

82.192

0.445
  comR Streptococcus pyogenes MGAS315

52.5

82.192

0.432
  comR Streptococcus mutans UA159

52.5

82.192

0.432
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

75.342

0.404
  comR Streptococcus suis P1/7

48.305

80.822

0.39
  comR Streptococcus suis 05ZYH33

48.305

80.822

0.39
  comR Streptococcus suis D9

47.458

80.822

0.384
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

46.491

78.082

0.363