Detailed information NTG0931556

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ACB335_RS01795
• Genome accession: NZ_CP167022
• Coordinates: 336729..337319 (+)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X9QW05
• Organism: Streptococcus pyogenes strain Isolate 4
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 331729..342319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB335_RS01780 (ACB335_01780)	-	332541..333986 (-)	1446	WP_031488572.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
ACB335_RS01785 (ACB335_01785)	-	334074..335708 (+)	1635	WP_031488573.1	polysaccharide biosynthesis protein	-
ACB335_RS01790 (ACB335_01790)	upp	335876..336505 (+)	630	WP_031488574.1	uracil phosphoribosyltransferase	-
ACB335_RS01795 (ACB335_01795)	clpP	336729..337319 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
ACB335_RS01800 (ACB335_01800)	-	337814..338089 (+)	276	WP_002985847.1	YlbG family protein	-
ACB335_RS01805 (ACB335_01805)	tmk	338338..338973 (+)	636	WP_014635306.1	dTMP kinase	-
ACB335_RS01810 (ACB335_01810)	-	338991..339866 (+)	876	WP_011528291.1	DNA polymerase III subunit delta'	-
ACB335_RS01815 (ACB335_01815)	-	339991..340125 (+)	135	WP_014635307.1	tpl protein	-
ACB335_RS01820 (ACB335_01820)	yabA	340529..340852 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
ACB335_RS01825 (ACB335_01825)	rsmI	340857..341720 (+)	864	WP_021733048.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
ACB335_RS01830 (ACB335_01830)	-	341747..342139 (+)	393	WP_002985833.1	DUF5684 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=931556 ACB335_RS01795 WP_002985850.1 336729..337319(+) (clpP) [Streptococcus pyogenes strain Isolate 4]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=931556 ACB335_RS01795 WP_002985850.1 336729..337319(+) (clpP) [Streptococcus pyogenes strain Isolate 4]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A9X9QW05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561