Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   ACB327_RS04940 Genome accession   NZ_CP167020
Coordinates   979764..979952 (-) Length   62 a.a.
NCBI ID   WP_011054546.1    Uniprot ID   A0A0H2UUN1
Organism   Streptococcus pyogenes strain Isolate 6     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 974764..984952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB327_RS04915 (ACB327_04915) - 976564..976935 (+) 372 WP_002989617.1 GntR family transcriptional regulator -
  ACB327_RS04920 (ACB327_04920) - 976935..977633 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  ACB327_RS04925 (ACB327_04925) - 977643..978428 (+) 786 WP_002984433.1 hypothetical protein -
  ACB327_RS04930 (ACB327_04930) - 978559..979173 (-) 615 WP_129322707.1 TVP38/TMEM64 family protein -
  ACB327_RS04940 (ACB327_04940) prx 979764..979952 (-) 189 WP_011054546.1 hypothetical protein Regulator
  ACB327_RS04945 (ACB327_04945) spel 980067..980855 (-) 789 WP_021340779.1 streptococcal pyrogenic exotoxin SpeL -
  ACB327_RS04950 (ACB327_04950) spem 981137..981817 (-) 681 WP_371400114.1 streptococcal pyrogenic exotoxin SpeM -
  ACB327_RS04955 (ACB327_04955) - 981786..982310 (-) 525 WP_129322709.1 Panacea domain-containing protein -
  ACB327_RS04960 (ACB327_04960) - 982449..983657 (-) 1209 WP_012560948.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7226.17 Da        Isoelectric Point: 3.9947

>NTDB_id=931389 ACB327_RS04940 WP_011054546.1 979764..979952(-) (prx) [Streptococcus pyogenes strain Isolate 6]
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=931389 ACB327_RS04940 WP_011054546.1 979764..979952(-) (prx) [Streptococcus pyogenes strain Isolate 6]
ATGCTAACATACGACGAATTTAAGCAAGCTATTGATGACGGATATATCGTAGGAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAGGAAGCGAGAAATGGAGAAGTTGTGACAGAGGAGAAGGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UUN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1
  prx Streptococcus pyogenes MGAS315

84.746

95.161

0.806
  prx Streptococcus pyogenes MGAS8232

84.483

93.548

0.79
  prx Streptococcus pyogenes MGAS315

82.759

93.548

0.774
  prx Streptococcus pyogenes MGAS315

77.966

95.161

0.742
  prx Streptococcus pyogenes MGAS315

87.805

66.129

0.581
  prx Streptococcus pyogenes MGAS315

76.19

67.742

0.516