Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   ACB352_RS03425 Genome accession   NZ_CP167009
Coordinates   650282..650464 (+) Length   60 a.a.
NCBI ID   WP_002986897.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 22     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 645282..655464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB352_RS03375 (ACB352_03375) - 645326..645598 (+) 273 WP_011017397.1 hypothetical protein -
  ACB352_RS03380 (ACB352_03380) - 645595..645822 (+) 228 WP_000609113.1 phage holin -
  ACB352_RS03385 (ACB352_03385) - 645938..647140 (+) 1203 WP_023611747.1 glucosaminidase domain-containing protein -
  ACB352_RS03390 (ACB352_03390) - 647327..647566 (-) 240 WP_003055855.1 hypothetical protein -
  ACB352_RS03395 (ACB352_03395) - 647635..647850 (-) 216 WP_023611751.1 hypothetical protein -
  ACB352_RS03400 (ACB352_03400) - 647852..648454 (-) 603 WP_023611748.1 AP endonuclease -
  ACB352_RS03405 (ACB352_03405) acrIIA3 648454..648828 (-) 375 WP_023611744.1 anti-CRISPR protein AcrIIA3 -
  ACB352_RS03410 (ACB352_03410) - 648961..649317 (-) 357 WP_003055891.1 hypothetical protein -
  ACB352_RS03415 (ACB352_03415) - 649319..649792 (-) 474 WP_076634523.1 hypothetical protein -
  ACB352_RS03420 (ACB352_03420) - 649832..650071 (-) 240 WP_002986898.1 hypothetical protein -
  ACB352_RS03425 (ACB352_03425) prx 650282..650464 (+) 183 WP_002986897.1 hypothetical protein Regulator
  ACB352_RS03430 (ACB352_03430) - 650709..651449 (+) 741 WP_011054725.1 response regulator -
  ACB352_RS03435 (ACB352_03435) - 651446..653179 (+) 1734 WP_011284967.1 sensor histidine kinase -
  ACB352_RS03440 (ACB352_03440) - 653252..654331 (+) 1080 WP_021341002.1 MmcQ/YjbR family DNA-binding protein -
  ACB352_RS03445 (ACB352_03445) - 654345..655061 (+) 717 WP_011284965.1 B3/4 domain-containing protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6772.68 Da        Isoelectric Point: 3.9286

>NTDB_id=930439 ACB352_RS03425 WP_002986897.1 650282..650464(+) (prx) [Streptococcus pyogenes strain Isolate 22]
MLTYDEFKQAIDDGYIVGDTVAIVRKNGQIFDYVLPGEKVRPSEVVAEEIVEEVVVELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=930439 ACB352_RS03425 WP_002986897.1 650282..650464(+) (prx) [Streptococcus pyogenes strain Isolate 22]
ATGCTAACATACGACGAGTTTAAGCAAGCAATCGATGACGGATATATCGTAGGAGACACAGTAGCGATTGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGCGAAAAAGTCAGACCGTCGGAGGTTGTGGCTGAGGAAATAGTGGAAGAGG
TGGTGGTGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

98.333

100

0.983

  prx Streptococcus pyogenes MGAS315

81.667

100

0.817

  prx Streptococcus pyogenes MGAS8232

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

73.333

100

0.733

  prx Streptococcus pyogenes MGAS315

90.244

68.333

0.617

  prx Streptococcus pyogenes MGAS315

82.927

68.333

0.567