Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   ACB353_RS07160 Genome accession   NZ_CP167008
Coordinates   1437457..1437639 (-) Length   60 a.a.
NCBI ID   WP_011054856.1    Uniprot ID   A0A0H2UW47
Organism   Streptococcus pyogenes strain Isolate 23     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 1432457..1442639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB353_RS07120 (ACB353_07120) - 1433736..1434137 (-) 402 WP_011284578.1 hypothetical protein -
  ACB353_RS07125 (ACB353_07125) - 1434316..1434612 (-) 297 WP_002985722.1 hypothetical protein -
  ACB353_RS07130 (ACB353_07130) - 1434662..1434790 (-) 129 WP_002985724.1 hypothetical protein -
  ACB353_RS07135 (ACB353_07135) - 1435151..1435351 (-) 201 WP_002985729.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACB353_RS07140 (ACB353_07140) - 1435364..1435591 (-) 228 WP_002992018.1 Blp family class II bacteriocin -
  ACB353_RS07145 (ACB353_07145) - 1435910..1436595 (+) 686 Protein_1351 transposase -
  ACB353_RS07150 (ACB353_07150) - 1436786..1436968 (-) 183 WP_002987564.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACB353_RS07155 (ACB353_07155) - 1436983..1437216 (-) 234 WP_011284576.1 bacteriocin class II family protein -
  ACB353_RS07160 (ACB353_07160) prx 1437457..1437639 (-) 183 WP_011054856.1 hypothetical protein Regulator
  ACB353_RS07165 (ACB353_07165) - 1437872..1438858 (+) 987 WP_011106647.1 DNA/RNA non-specific endonuclease -
  ACB353_RS07170 (ACB353_07170) - 1438972..1439487 (-) 516 WP_023077389.1 hypothetical protein -
  ACB353_RS07175 (ACB353_07175) - 1439809..1441011 (-) 1203 WP_011184057.1 glucosaminidase domain-containing protein -
  ACB353_RS07180 (ACB353_07180) - 1441127..1441354 (-) 228 WP_003058873.1 phage holin -
  ACB353_RS07185 (ACB353_07185) - 1441351..1441623 (-) 273 WP_002986916.1 hypothetical protein -
  ACB353_RS07190 (ACB353_07190) - 1441633..1442250 (-) 618 WP_011184056.1 DUF1366 domain-containing protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6927.67 Da        Isoelectric Point: 3.9286

>NTDB_id=930375 ACB353_RS07160 WP_011054856.1 1437457..1437639(-) (prx) [Streptococcus pyogenes strain Isolate 23]
MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYALPNEEVRNGEVVTYENVEEVLRELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=930375 ACB353_RS07160 WP_011054856.1 1437457..1437639(-) (prx) [Streptococcus pyogenes strain Isolate 23]
ATGCTAACATACGATGAGTTTAAGCAAGCTATTGATGACGGATATATCACAGGCGACACAGTGGCGATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGCGTTGCCGAATGAAGAGGTAAGAAATGGGGAGGTTGTAACATACGAAAATGTGGAAGAAG
TGCTGAGGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UW47

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS8232

80

100

0.8

  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

75

100

0.75

  prx Streptococcus pyogenes MGAS315

88.372

71.667

0.633

  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6

  prx Streptococcus pyogenes MGAS315

76.19

70

0.533