Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ACB356_RS08525 Genome accession   NZ_CP166998
Coordinates   1723965..1724561 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes strain Isolate 35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1718965..1729561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB356_RS08490 (ACB356_08490) - 1719026..1719331 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ACB356_RS08495 (ACB356_08495) ruvX 1719343..1719762 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ACB356_RS08500 (ACB356_08500) - 1719759..1720028 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ACB356_RS08505 (ACB356_08505) spx 1720141..1720539 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ACB356_RS08510 (ACB356_08510) recA 1720830..1721966 (-) 1137 WP_002982186.1 recombinase RecA Machinery gene
  ACB356_RS08515 (ACB356_08515) cinA 1722055..1723326 (-) 1272 WP_002991356.1 competence/damage-inducible protein A Machinery gene
  ACB356_RS08520 (ACB356_08520) - 1723395..1723955 (-) 561 WP_002991358.1 DNA-3-methyladenine glycosylase I -
  ACB356_RS08525 (ACB356_08525) ruvA 1723965..1724561 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  ACB356_RS08530 (ACB356_08530) - 1724563..1725784 (-) 1222 Protein_1619 MDR family MFS transporter -
  ACB356_RS08535 (ACB356_08535) hexB 1725795..1727777 (-) 1983 WP_002991363.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=929439 ACB356_RS08525 WP_002991359.1 1723965..1724561(-) (ruvA) [Streptococcus pyogenes strain Isolate 35]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=929439 ACB356_RS08525 WP_002991359.1 1723965..1724561(-) (ruvA) [Streptococcus pyogenes strain Isolate 35]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424