NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	VKP36_RS01770	Genome accession	NZ_CP142357
Coordinates	332232..332822 (+)	Length	196 a.a.
NCBI ID	WP_002985850.1	Uniprot ID	A0A9X8T4H8
Organism	Streptococcus pyogenes strain AW-534
Function	degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 327232..337822

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP36_RS01755 (VKP36_01755)	-	328044..329489 (-)	1446	WP_326625098.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
VKP36_RS01760 (VKP36_01760)	-	329577..331211 (+)	1635	WP_011284531.1	polysaccharide biosynthesis protein	-
VKP36_RS01765 (VKP36_01765)	upp	331379..332008 (+)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
VKP36_RS01770 (VKP36_01770)	clpP	332232..332822 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
VKP36_RS01775 (VKP36_01775)	-	333314..333589 (+)	276	WP_002985847.1	YlbG family protein	-
VKP36_RS01780 (VKP36_01780)	tmk	333838..334473 (+)	636	WP_010921930.1	dTMP kinase	-
VKP36_RS01785 (VKP36_01785)	-	334491..335366 (+)	876	WP_109828778.1	DNA polymerase III subunit delta'	-
VKP36_RS01790 (VKP36_01790)	yabA	335869..336192 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
VKP36_RS01795 (VKP36_01795)	rsmI	336197..337060 (+)	864	WP_111713923.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
VKP36_RS01800 (VKP36_01800)	-	337087..337479 (+)	393	WP_023609786.1	DUF5684 domain-containing protein	-

Sequence

Protein

Download Length: 196 a.a. Molecular weight: 21648.88 Da Isoelectric Point: 5.2834

                                >NTDB_id=925369 VKP36_RS01770 WP_002985850.1 332232..332822(+) (clpP) [Streptococcus pyogenes strain AW-534]

MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN

FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK

TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

Download Length: 591 bp

                                >NTDB_id=925369 VKP36_RS01770 WP_002985850.1 332232..332822(+) (clpP) [Streptococcus pyogenes strain AW-534]

ATGATTCCTGTTGTTATTGAACAAACTAGTCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT

TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA

ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC

TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA

AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA

CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCACAAAATGCTGGAAAA

ACGATTAAACAAATTCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA

TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561

Detailed information NTG0925369