Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   VKP54_RS05360 Genome accession   NZ_CP142356
Coordinates   1079021..1079203 (-) Length   60 a.a.
NCBI ID   WP_011184726.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain CT95-157     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1079021..1122048 1079021..1079203 within 0


Gene organization within MGE regions


Location: 1079021..1122048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP54_RS05360 (VKP54_05360) prx 1079021..1079203 (-) 183 WP_011184726.1 hypothetical protein Regulator
  VKP54_RS05365 (VKP54_05365) mf2 1079443..1080201 (+) 759 WP_011184727.1 DNase Mf2 -
  VKP54_RS05370 (VKP54_05370) speC 1080312..1081019 (+) 708 WP_002985327.1 streptococcal pyrogenic exotoxin SpeC -
  VKP54_RS05375 (VKP54_05375) - 1081088..1081840 (-) 753 WP_023611694.1 CHAP domain-containing protein -
  VKP54_RS05380 (VKP54_05380) - 1081842..1082174 (-) 333 WP_003052353.1 phage holin -
  VKP54_RS05385 (VKP54_05385) - 1082176..1082505 (-) 330 WP_111694880.1 hypothetical protein -
  VKP54_RS05390 (VKP54_05390) - 1082516..1083127 (-) 612 WP_111694881.1 DUF1366 domain-containing protein -
  VKP54_RS05395 (VKP54_05395) - 1083130..1083558 (-) 429 WP_111694882.1 DUF1617 family protein -
  VKP54_RS05400 (VKP54_05400) - 1083567..1085390 (-) 1824 WP_111711359.1 gp58-like family protein -
  VKP54_RS05405 (VKP54_05405) - 1085401..1085715 (-) 315 WP_063812987.1 hypothetical protein -
  VKP54_RS05410 (VKP54_05410) - 1085717..1086940 (-) 1224 WP_030127718.1 hypothetical protein -
  VKP54_RS05415 (VKP54_05415) - 1086937..1089084 (-) 2148 WP_111694884.1 phage tail spike protein -
  VKP54_RS05420 (VKP54_05420) - 1089081..1089797 (-) 717 WP_111674636.1 distal tail protein Dit -
  VKP54_RS05425 (VKP54_05425) - 1089794..1093054 (-) 3261 WP_129820702.1 tape measure protein -
  VKP54_RS05430 (VKP54_05430) - 1093044..1093625 (-) 582 WP_010922087.1 bacteriophage Gp15 family protein -
  VKP54_RS05435 (VKP54_05435) - 1093629..1094063 (-) 435 WP_010922086.1 hypothetical protein -
  VKP54_RS05440 (VKP54_05440) - 1094116..1094586 (-) 471 WP_011527917.1 phage tail tube protein -
  VKP54_RS05445 (VKP54_05445) - 1094586..1094984 (-) 399 WP_010922084.1 minor capsid protein -
  VKP54_RS05450 (VKP54_05450) - 1094981..1095337 (-) 357 WP_010922083.1 minor capsid protein -
  VKP54_RS05455 (VKP54_05455) - 1095337..1095669 (-) 333 WP_010922082.1 minor capsid protein -
  VKP54_RS05460 (VKP54_05460) - 1095659..1096075 (-) 417 WP_111694886.1 hypothetical protein -
  VKP54_RS05465 (VKP54_05465) - 1096129..1096947 (-) 819 WP_111711357.1 N4-gp56 family major capsid protein -
  VKP54_RS05470 (VKP54_05470) - 1096951..1097565 (-) 615 WP_010922079.1 hypothetical protein -
  VKP54_RS05475 (VKP54_05475) - 1097691..1097957 (-) 267 WP_111694887.1 hypothetical protein -
  VKP54_RS05480 (VKP54_05480) - 1098019..1098258 (-) 240 WP_002986829.1 hypothetical protein -
  VKP54_RS05485 (VKP54_05485) - 1098230..1099708 (-) 1479 WP_326612731.1 phage minor capsid protein -
  VKP54_RS05490 (VKP54_05490) - 1099713..1101215 (-) 1503 WP_010922075.1 phage portal protein -
  VKP54_RS05495 (VKP54_05495) - 1101229..1102524 (-) 1296 WP_165363098.1 PBSX family phage terminase large subunit -
  VKP54_RS05500 (VKP54_05500) terS 1102517..1103212 (-) 696 WP_050318691.1 phage terminase small subunit -
  VKP54_RS05505 (VKP54_05505) - 1103332..1103748 (-) 417 WP_011054881.1 transcriptional regulator -
  VKP54_RS05510 (VKP54_05510) - 1103881..1104153 (-) 273 WP_011054882.1 hypothetical protein -
  VKP54_RS05515 (VKP54_05515) - 1104146..1104316 (-) 171 WP_164972002.1 hypothetical protein -
  VKP54_RS05520 (VKP54_05520) - 1104317..1105639 (-) 1323 WP_111694889.1 SNF2-related protein -
  VKP54_RS05525 (VKP54_05525) - 1105636..1105911 (-) 276 WP_129820701.1 VRR-NUC domain-containing protein -
  VKP54_RS05530 (VKP54_05530) - 1106297..1108681 (-) 2385 WP_111688312.1 phage/plasmid primase, P4 family -
  VKP54_RS05535 (VKP54_05535) - 1108686..1110608 (-) 1923 WP_111674645.1 DNA polymerase -
  VKP54_RS05540 (VKP54_05540) - 1110651..1111214 (-) 564 WP_111674646.1 DUF2815 family protein -
  VKP54_RS05545 (VKP54_05545) - 1111223..1112380 (-) 1158 WP_023611034.1 DUF2800 domain-containing protein -
  VKP54_RS05550 (VKP54_05550) - 1112380..1112679 (-) 300 WP_002988708.1 hypothetical protein -
  VKP54_RS05555 (VKP54_05555) - 1112768..1112971 (-) 204 WP_023611025.1 hypothetical protein -
  VKP54_RS05560 (VKP54_05560) - 1113461..1113847 (-) 387 WP_111694890.1 hypothetical protein -
  VKP54_RS05565 (VKP54_05565) - 1113844..1114060 (-) 217 Protein_1058 hypothetical protein -
  VKP54_RS05570 (VKP54_05570) - 1114053..1114223 (-) 171 WP_023611037.1 hypothetical protein -
  VKP54_RS05575 (VKP54_05575) - 1114225..1114536 (-) 312 WP_014411880.1 hypothetical protein -
  VKP54_RS05580 (VKP54_05580) - 1114643..1114858 (+) 216 WP_023611028.1 hypothetical protein -
  VKP54_RS05585 (VKP54_05585) - 1114832..1115080 (-) 249 WP_023611035.1 hypothetical protein -
  VKP54_RS05590 (VKP54_05590) - 1115160..1115369 (+) 210 WP_011017885.1 hypothetical protein -
  VKP54_RS05595 (VKP54_05595) - 1115511..1115771 (+) 261 WP_023611024.1 hypothetical protein -
  VKP54_RS05600 (VKP54_05600) - 1115870..1116523 (-) 654 WP_111688314.1 phage antirepressor KilAC domain-containing protein -
  VKP54_RS05605 (VKP54_05605) - 1116535..1116726 (-) 192 WP_002993390.1 hypothetical protein -
  VKP54_RS05610 (VKP54_05610) - 1117362..1117457 (+) 96 WP_020837421.1 type I toxin-antitoxin system Fst family toxin -
  VKP54_RS05615 (VKP54_05615) - 1117879..1118226 (+) 348 WP_111688316.1 helix-turn-helix domain-containing protein -
  VKP54_RS05620 (VKP54_05620) - 1118230..1118610 (+) 381 WP_111711356.1 ImmA/IrrE family metallo-endopeptidase -
  VKP54_RS05625 (VKP54_05625) - 1118622..1118888 (+) 267 WP_076634078.1 DUF4177 domain-containing protein -
  VKP54_RS05630 (VKP54_05630) - 1119017..1120159 (+) 1143 WP_003051793.1 tyrosine-type recombinase/integrase -
  VKP54_RS05635 (VKP54_05635) - 1120249..1120524 (-) 276 WP_002983920.1 HU family DNA-binding protein -
  VKP54_RS05640 (VKP54_05640) - 1120623..1121210 (-) 588 WP_111711355.1 YpmS family protein -
  VKP54_RS05645 (VKP54_05645) - 1121188..1122030 (-) 843 WP_002992620.1 SGNH/GDSL hydrolase family protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6936.91 Da        Isoelectric Point: 4.1954

>NTDB_id=925331 VKP54_RS05360 WP_011184726.1 1079021..1079203(-) (prx) [Streptococcus pyogenes strain CT95-157]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPNEKIKNGEIVTDEKVEEVLVELSR

Nucleotide


Download         Length: 183 bp        

>NTDB_id=925331 VKP54_RS05360 WP_011184726.1 1079021..1079203(-) (prx) [Streptococcus pyogenes strain CT95-157]
ATGCTAACATACGACGAATTTAAACAAGCAATTGACAATGGATATATCACAGCAGACACAGTAATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGAATGAGAAGATAAAGAATGGAGAAATTGTGACAGACGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

98.333

100

0.983
  prx Streptococcus pyogenes MGAS8232

86.667

100

0.867
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783
  prx Streptococcus pyogenes MGAS315

75

100

0.75
  prx Streptococcus pyogenes MGAS315

83.721

71.667

0.6
  prx Streptococcus pyogenes MGAS315

85.366

68.333

0.583
  prx Streptococcus pyogenes MGAS315

71.429

70

0.5