Detailed information NTG0925109

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VKP38_RS04780
• Genome accession: NZ_CP142352
• Coordinates: 933073..933909 (-)
• Length: 278 a.a.
• NCBI ID: WP_032464378.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 2907-97
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 928073..938909

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP38_RS04770 (VKP38_04770)	trmFO	929356..930702 (-)	1347	WP_326603998.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
VKP38_RS04775 (VKP38_04775)	topA	930837..932966 (-)	2130	WP_032464379.1	type I DNA topoisomerase	-
VKP38_RS04780 (VKP38_04780)	dprA	933073..933909 (-)	837	WP_032464378.1	DNA-processing protein DprA	Machinery gene
VKP38_RS04785 (VKP38_04785)	-	933974..934765 (-)	792	WP_011888871.1	ribonuclease HII	-
VKP38_RS04790 (VKP38_04790)	ylqF	934755..935603 (-)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
VKP38_RS04795 (VKP38_04795)	-	935822..936262 (+)	441	WP_002984627.1	DUF1836 domain-containing protein	-
VKP38_RS04800 (VKP38_04800)	trhA	936259..936909 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
VKP38_RS04805 (VKP38_04805)	-	937026..937937 (+)	912	WP_326604523.1	diacylglycerol kinase family protein	-
VKP38_RS04810 (VKP38_04810)	-	937987..938442 (-)	456	WP_326604525.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31088.08 Da
• Isoelectric Point: 9.0513

>NTDB_id=925109 VKP38_RS04780 WP_032464378.1 933073..933909(-) (dprA) [Streptococcus pyogenes strain 2907-97]
MNHFELYKLKKARLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=925109 VKP38_RS04780 WP_032464378.1 933073..933909(-) (dprA) [Streptococcus pyogenes strain 2907-97]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTAGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Acinetobacter baumannii strain A118	35.395	100	0.371
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367