Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   VKP55_RS05450 Genome accession   NZ_CP142351
Coordinates   1099024..1099206 (-) Length   60 a.a.
NCBI ID   WP_011184726.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain SS1366     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1099024..1134348 1099024..1099206 within 0


Gene organization within MGE regions


Location: 1099024..1134348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP55_RS05450 (VKP55_05450) prx 1099024..1099206 (-) 183 WP_011184726.1 hypothetical protein Regulator
  VKP55_RS05455 (VKP55_05455) mf2 1099446..1100204 (+) 759 WP_011184727.1 DNase Mf2 -
  VKP55_RS05460 (VKP55_05460) speC 1100315..1101022 (+) 708 WP_002985327.1 streptococcal pyrogenic exotoxin SpeC -
  VKP55_RS05465 (VKP55_05465) - 1101091..1102308 (-) 1218 WP_014635574.1 peptidoglycan amidohydrolase family protein -
  VKP55_RS05470 (VKP55_05470) - 1102427..1102654 (-) 228 WP_003058873.1 phage holin -
  VKP55_RS05475 (VKP55_05475) - 1102651..1102923 (-) 273 WP_011017397.1 hypothetical protein -
  VKP55_RS05480 (VKP55_05480) - 1102935..1103567 (-) 633 WP_011528779.1 hypothetical protein -
  VKP55_RS05485 (VKP55_05485) - 1103570..1103998 (-) 429 WP_136266864.1 DUF1617 family protein -
  VKP55_RS05490 (VKP55_05490) - 1104007..1105788 (-) 1782 WP_063662161.1 gp58-like family protein -
  VKP55_RS05495 (VKP55_05495) - 1105803..1106918 (-) 1116 WP_063662158.1 hyaluronoglucosaminidase -
  VKP55_RS05500 (VKP55_05500) - 1106918..1108891 (-) 1974 WP_168434316.1 phage tail spike protein -
  VKP55_RS05505 (VKP55_05505) - 1108873..1109568 (-) 696 WP_002992579.1 hypothetical protein -
  VKP55_RS05510 (VKP55_05510) - 1109565..1111373 (-) 1809 WP_326673887.1 hypothetical protein -
  VKP55_RS05515 (VKP55_05515) - 1111581..1112141 (-) 561 WP_011017973.1 HNH endonuclease -
  VKP55_RS05520 (VKP55_05520) - 1112314..1112841 (-) 528 Protein_1047 hypothetical protein -
  VKP55_RS05525 (VKP55_05525) - 1112841..1113212 (-) 372 WP_011054678.1 DUF5361 domain-containing protein -
  VKP55_RS05530 (VKP55_05530) - 1113227..1113490 (-) 264 WP_010922455.1 hypothetical protein -
  VKP55_RS05535 (VKP55_05535) - 1113501..1114091 (-) 591 WP_021733477.1 hypothetical protein -
  VKP55_RS05540 (VKP55_05540) - 1114107..1114442 (-) 336 WP_021733481.1 hypothetical protein -
  VKP55_RS05545 (VKP55_05545) - 1114443..1114679 (-) 237 WP_000032787.1 hypothetical protein -
  VKP55_RS05550 (VKP55_05550) - 1114672..1115010 (-) 339 WP_011054681.1 hypothetical protein -
  VKP55_RS05555 (VKP55_05555) - 1114970..1115392 (-) 423 WP_021733479.1 phage Gp19/Gp15/Gp42 family protein -
  VKP55_RS05560 (VKP55_05560) - 1115402..1115602 (-) 201 WP_010922460.1 hypothetical protein -
  VKP55_RS05565 (VKP55_05565) - 1115602..1116513 (-) 912 WP_011054683.1 phage major capsid protein -
  VKP55_RS05570 (VKP55_05570) - 1116538..1116999 (-) 462 WP_010922462.1 DUF4355 domain-containing protein -
  VKP55_RS05575 (VKP55_05575) - 1117081..1118496 (-) 1416 WP_021299324.1 phage terminase large subunit-like protein -
  VKP55_RS05580 (VKP55_05580) - 1118560..1118829 (-) 270 WP_002994096.1 hypothetical protein -
  VKP55_RS05585 (VKP55_05585) - 1118822..1119001 (-) 180 WP_326674550.1 hypothetical protein -
  VKP55_RS05590 (VKP55_05590) - 1119051..1119275 (-) 225 WP_326673894.1 hypothetical protein -
  VKP55_RS05595 (VKP55_05595) - 1119281..1120774 (-) 1494 WP_326673896.1 hypothetical protein -
  VKP55_RS05600 (VKP55_05600) - 1120767..1122035 (-) 1269 WP_011017979.1 phage portal protein -
  VKP55_RS05605 (VKP55_05605) - 1122032..1122388 (-) 357 WP_109828582.1 hypothetical protein -
  VKP55_RS05610 (VKP55_05610) - 1122537..1122881 (-) 345 WP_010922469.1 HNH endonuclease signature motif containing protein -
  VKP55_RS05615 (VKP55_05615) - 1122991..1123410 (-) 420 WP_021733384.1 DUF1492 domain-containing protein -
  VKP55_RS05620 (VKP55_05620) - 1123676..1123846 (-) 171 WP_168389619.1 hypothetical protein -
  VKP55_RS05625 (VKP55_05625) - 1123851..1124036 (-) 186 WP_011017985.1 hypothetical protein -
  VKP55_RS05630 (VKP55_05630) - 1124023..1124535 (-) 513 WP_011888758.1 hypothetical protein -
  VKP55_RS05635 (VKP55_05635) - 1124532..1124873 (-) 342 WP_011888757.1 hypothetical protein -
  VKP55_RS05640 (VKP55_05640) - 1125069..1126097 (-) 1029 WP_011888756.1 DUF1351 domain-containing protein -
  VKP55_RS05645 (VKP55_05645) bet 1126107..1126883 (-) 777 WP_011888755.1 phage recombination protein Bet -
  VKP55_RS05650 (VKP55_05650) - 1126886..1127215 (-) 330 WP_011888754.1 hypothetical protein -
  VKP55_RS05655 (VKP55_05655) - 1127271..1127477 (-) 207 WP_011017565.1 hypothetical protein -
  VKP55_RS05660 (VKP55_05660) - 1127486..1127626 (-) 141 WP_011017992.1 hypothetical protein -
  VKP55_RS05665 (VKP55_05665) - 1127623..1127856 (-) 234 WP_002985387.1 hypothetical protein -
  VKP55_RS05670 (VKP55_05670) - 1127837..1128223 (-) 387 WP_002985388.1 DnaD domain-containing protein -
  VKP55_RS05675 (VKP55_05675) - 1128363..1128632 (-) 270 WP_038433488.1 replication protein -
  VKP55_RS05680 (VKP55_05680) - 1128726..1128911 (-) 186 WP_326673905.1 hypothetical protein -
  VKP55_RS05685 (VKP55_05685) - 1128913..1129224 (-) 312 WP_010922478.1 excisionase -
  VKP55_RS05690 (VKP55_05690) - 1129494..1129706 (-) 213 WP_010922479.1 helix-turn-helix domain-containing protein -
  VKP55_RS05695 (VKP55_05695) - 1129908..1130663 (+) 756 WP_010922480.1 helix-turn-helix domain-containing protein -
  VKP55_RS05700 (VKP55_05700) - 1130675..1131193 (+) 519 WP_326673907.1 HIRAN domain-containing protein -
  VKP55_RS05705 (VKP55_05705) - 1131317..1132459 (+) 1143 WP_115223139.1 tyrosine-type recombinase/integrase -
  VKP55_RS05710 (VKP55_05710) - 1132549..1132824 (-) 276 WP_002983920.1 HU family DNA-binding protein -
  VKP55_RS05715 (VKP55_05715) - 1132923..1133510 (-) 588 WP_002989129.1 YpmS family protein -
  VKP55_RS05720 (VKP55_05720) - 1133488..1134330 (-) 843 WP_002992620.1 SGNH/GDSL hydrolase family protein -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6936.91 Da        Isoelectric Point: 4.1954

>NTDB_id=925056 VKP55_RS05450 WP_011184726.1 1099024..1099206(-) (prx) [Streptococcus pyogenes strain SS1366]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPNEKIKNGEIVTDEKVEEVLVELSR

Nucleotide


Download         Length: 183 bp        

>NTDB_id=925056 VKP55_RS05450 WP_011184726.1 1099024..1099206(-) (prx) [Streptococcus pyogenes strain SS1366]
ATGCTAACATACGACGAATTTAAACAAGCAATTGACAATGGATATATCACAGCAGACACAGTAATGATCGTGCGCAAGAA
CGGACAGATTTTTGATTATGTGTTGCCGAATGAGAAGATAAAGAATGGAGAAATTGTGACAGACGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

98.333

100

0.983
  prx Streptococcus pyogenes MGAS8232

86.667

100

0.867
  prx Streptococcus pyogenes MGAS315

78.333

100

0.783
  prx Streptococcus pyogenes MGAS315

75

100

0.75
  prx Streptococcus pyogenes MGAS315

83.721

71.667

0.6
  prx Streptococcus pyogenes MGAS315

85.366

68.333

0.583
  prx Streptococcus pyogenes MGAS315

71.429

70

0.5