Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   VOI49_RS03120 Genome accession   NZ_CP142018
Coordinates   574923..575633 (+) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae strain lu24     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 569923..580633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS03090 - 569926..570921 (+) 996 WP_003049945.1 DUF3114 domain-containing protein -
  VOI49_RS03095 - 571096..571461 (+) 366 WP_411576842.1 DDE-type integrase/transposase/recombinase -
  VOI49_RS03100 - 571694..572341 (-) 648 WP_003049948.1 amino acid ABC transporter permease -
  VOI49_RS03105 - 572356..573057 (-) 702 WP_003049949.1 amino acid ABC transporter permease -
  VOI49_RS03110 - 573071..573871 (-) 801 WP_003049950.1 transporter substrate-binding domain-containing protein -
  VOI49_RS03115 - 573871..574665 (-) 795 WP_003049951.1 amino acid ABC transporter ATP-binding protein -
  VOI49_RS03120 vicR 574923..575633 (+) 711 WP_003049952.1 response regulator YycF Regulator
  VOI49_RS03125 vicK 575626..576978 (+) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  VOI49_RS03130 vicX 576982..577791 (+) 810 WP_115252716.1 MBL fold metallo-hydrolase Regulator
  VOI49_RS03135 rnc 577890..578582 (+) 693 WP_003049954.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=921012 VOI49_RS03120 WP_003049952.1 574923..575633(+) (vicR) [Streptococcus dysgalactiae strain lu24]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=921012 VOI49_RS03120 WP_003049952.1 574923..575633(+) (vicR) [Streptococcus dysgalactiae strain lu24]
ATGAAAAAAATACTGATTGTGGATGATGAGAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGAGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAAGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACTATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTGGACGTGACAGTTCGCCGCCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377