Detailed information NTG0921013

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: VOI49_RS03125
• Genome accession: NZ_CP142018
• Coordinates: 575626..576978 (+)
• Length: 450 a.a.
• NCBI ID: WP_003049953.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain lu24
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 570626..581978

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOI49_RS03095	-	571096..571461 (+)	366	WP_411576842.1	DDE-type integrase/transposase/recombinase	-
VOI49_RS03100	-	571694..572341 (-)	648	WP_003049948.1	amino acid ABC transporter permease	-
VOI49_RS03105	-	572356..573057 (-)	702	WP_003049949.1	amino acid ABC transporter permease	-
VOI49_RS03110	-	573071..573871 (-)	801	WP_003049950.1	transporter substrate-binding domain-containing protein	-
VOI49_RS03115	-	573871..574665 (-)	795	WP_003049951.1	amino acid ABC transporter ATP-binding protein	-
VOI49_RS03120	vicR	574923..575633 (+)	711	WP_003049952.1	response regulator YycF	Regulator
VOI49_RS03125	vicK	575626..576978 (+)	1353	WP_003049953.1	cell wall metabolism sensor histidine kinase VicK	Regulator
VOI49_RS03130	vicX	576982..577791 (+)	810	WP_115252716.1	MBL fold metallo-hydrolase	Regulator
VOI49_RS03135	rnc	577890..578582 (+)	693	WP_003049954.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.02 Da
• Isoelectric Point: 5.5557

>NTDB_id=921013 VOI49_RS03125 WP_003049953.1 575626..576978(+) (vicK) [Streptococcus dysgalactiae strain lu24]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=921013 VOI49_RS03125 WP_003049953.1 575626..576978(+) (vicK) [Streptococcus dysgalactiae strain lu24]
ATGACTAGAGATATCATCGGGAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAATGAGAAGGCGGACATTGAATTGATGGAACTGGCAGATCAGTTAAATGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTTAATCTGACCAAGGAGCAGG
CTCTTGAAAAGAACATTACCGATTTGCTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGTTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGAATGATTTCTGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTCACAGCTTTTATGACGTCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGATTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCAATTAAATACTCTCCTGA
TGGTGGAAAGATTACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGTCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-165)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.671	92	0.678
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631