Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   U5U21_RS18130 Genome accession   NZ_CP140722
Coordinates   3172591..3173172 (+) Length   193 a.a.
NCBI ID   WP_000991625.1    Uniprot ID   A0A2A8KY00
Organism   Bacillus anthracis strain MH-VW     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3167591..3178172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U5U21_RS18100 (U5U21_18165) - 3167810..3168328 (+) 519 WP_000720568.1 DNA topology modulation protein -
  U5U21_RS18105 (U5U21_18170) - 3168766..3170133 (+) 1368 WP_001065250.1 lytic polysaccharide monooxygenase -
  U5U21_RS18110 (U5U21_18175) - 3170264..3170698 (-) 435 WP_000555717.1 GNAT family N-acetyltransferase -
  U5U21_RS18115 (U5U21_18180) rpiA 3170806..3171468 (-) 663 WP_000364536.1 ribose 5-phosphate isomerase A -
  U5U21_RS18120 (U5U21_18185) - 3171473..3171739 (-) 267 WP_001125370.1 2Fe-2S iron-sulfur cluster-binding protein -
  U5U21_RS18125 (U5U21_18190) - 3171883..3172569 (+) 687 WP_000337487.1 RNA polymerase subunit sigma-70 -
  U5U21_RS18130 (U5U21_18195) clpP 3172591..3173172 (+) 582 WP_000991625.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  U5U21_RS18135 (U5U21_18200) - 3173218..3174074 (-) 857 Protein_3273 glycine betaine ABC transporter substrate-binding protein -
  U5U21_RS18140 (U5U21_18205) - 3174246..3175451 (+) 1206 WP_000370609.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  U5U21_RS18145 (U5U21_18210) - 3175444..3176280 (+) 837 WP_001084757.1 proline/glycine betaine ABC transporter permease -
  U5U21_RS18150 (U5U21_18215) - 3176757..3176924 (+) 168 WP_000508407.1 hypothetical protein -
  U5U21_RS18155 (U5U21_18220) - 3177039..3177863 (+) 825 WP_000557567.1 PP2C family serine/threonine-protein phosphatase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21178.42 Da        Isoelectric Point: 5.0776

>NTDB_id=915170 U5U21_RS18130 WP_000991625.1 3172591..3173172(+) (clpP) [Bacillus anthracis strain MH-VW]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=915170 U5U21_RS18130 WP_000991625.1 3172591..3173172(+) (clpP) [Bacillus anthracis strain MH-VW]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATACTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTAGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCTATATTAGATACG
ATGAATTTAATTAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCGCAAGGGCAAGCGA
CGGAAATCGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A8KY00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

66.667

97.927

0.653
  clpP Streptococcus thermophilus LMD-9

54.688

99.482

0.544
  clpP Streptococcus pneumoniae Rx1

54.688

99.482

0.544
  clpP Streptococcus thermophilus LMG 18311

54.688

99.482

0.544
  clpP Streptococcus pneumoniae D39

54.688

99.482

0.544
  clpP Streptococcus pneumoniae R6

54.688

99.482

0.544
  clpP Streptococcus pneumoniae TIGR4

54.688

99.482

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

53.439

97.927

0.523
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

49.735

97.927

0.487