Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   L6411_RS00805 Genome accession   NZ_AP025333
Coordinates   125628..125921 (+) Length   97 a.a.
NCBI ID   WP_155963927.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 120628..130921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS00775 (GUT189_01220) - 121559..121927 (+) 369 WP_155962601.1 DUF1033 family protein -
  L6411_RS00780 (GUT189_01230) - 121965..122915 (-) 951 WP_155974247.1 S66 family peptidase -
  L6411_RS00785 (GUT189_01240) comYA 123076..124026 (+) 951 WP_155962599.1 competence type IV pilus ATPase ComGA Machinery gene
  L6411_RS00790 (GUT189_01250) comYB 123947..124978 (+) 1032 WP_272877484.1 competence type IV pilus assembly protein ComGB Machinery gene
  L6411_RS00795 (GUT189_01260) comYC 124975..125256 (+) 282 WP_237374201.1 competence type IV pilus major pilin ComGC Machinery gene
  L6411_RS00800 (GUT189_01270) comGD 125243..125656 (+) 414 WP_237374202.1 competence type IV pilus minor pilin ComGD -
  L6411_RS00805 (GUT189_01280) comYE 125628..125921 (+) 294 WP_155963927.1 competence type IV pilus minor pilin ComGE Machinery gene
  L6411_RS00810 (GUT189_01290) comGF/cglF 125908..126342 (+) 435 WP_237374203.1 competence type IV pilus minor pilin ComGF Machinery gene
  L6411_RS00815 (GUT189_01300) comGG 126320..126733 (+) 414 WP_120171207.1 competence type IV pilus minor pilin ComGG -
  L6411_RS00820 (GUT189_01310) comYH 126738..127691 (+) 954 WP_237374204.1 class I SAM-dependent methyltransferase Machinery gene
  L6411_RS00825 (GUT189_01320) - 127741..128928 (+) 1188 WP_024532248.1 acetate kinase -
  L6411_RS00830 (GUT189_01330) - 129233..129787 (+) 555 WP_024532247.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10898.87 Da        Isoelectric Point: 10.4805

>NTDB_id=91222 L6411_RS00805 WP_155963927.1 125628..125921(+) (comYE) [Streptococcus ruminantium strain GUT-189]
MVVIKNQKNKAYVLLESLVALAVFVAICSLLLSAITTGRRRQAWELKQQEILNLAQMAVQTKQHHLVLNGVEVTVQRSSN
QLVVFHEGKEVLHIAKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=91222 L6411_RS00805 WP_155963927.1 125628..125921(+) (comYE) [Streptococcus ruminantium strain GUT-189]
GTGGTCGTTATAAAAAATCAGAAGAATAAGGCCTATGTTTTGCTAGAAAGTTTGGTAGCTTTGGCGGTCTTTGTTGCTAT
TTGTAGCTTGCTTCTATCAGCTATAACTACTGGCCGGAGGCGTCAGGCTTGGGAATTAAAACAACAGGAAATTCTCAATC
TGGCTCAGATGGCTGTGCAGACCAAGCAACATCATTTGGTACTCAATGGTGTGGAGGTGACTGTACAACGGAGTTCAAAT
CAATTAGTCGTTTTTCACGAAGGGAAGGAGGTTTTGCACATTGCTAAAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

52.083

98.969

0.515
  comYE Streptococcus mutans UA159

52.083

98.969

0.515
  comGE/cglE Streptococcus mitis SK321

42.857

93.814

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

42.857

93.814

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae Rx1

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae R6

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae TIGR4

41.758

93.814

0.392
  comGE Lactococcus lactis subsp. cremoris KW2

37.234

96.907

0.361

Multiple sequence alignment