Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   L6411_RS00370 Genome accession   NZ_AP025333
Coordinates   56536..57906 (+) Length   456 a.a.
NCBI ID   WP_336512685.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 51536..62906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS00330 (GUT189_00470) - 51656..51808 (+) 153 WP_155962529.1 hypothetical protein -
  L6411_RS09925 - 52475..52606 (+) 132 WP_257875343.1 hypothetical protein -
  L6411_RS00335 (GUT189_00480) - 52816..53010 (+) 195 WP_155963542.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6411_RS00340 (GUT189_00490) - 53025..53213 (+) 189 WP_155963541.1 hypothetical protein -
  L6411_RS00345 (GUT189_00500) - 53217..53372 (+) 156 WP_155963540.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6411_RS00350 (GUT189_00510) - 53426..53617 (+) 192 WP_024533166.1 hypothetical protein -
  L6411_RS00355 (GUT189_00520) - 53731..53898 (+) 168 WP_237374188.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  L6411_RS00360 - 53885..54031 (+) 147 WP_156019613.1 hypothetical protein -
  L6411_RS00365 (GUT189_00530) comA 54377..56530 (+) 2154 WP_120171173.1 peptide cleavage/export ABC transporter ComA Regulator
  L6411_RS00370 (GUT189_00540) comB 56536..57906 (+) 1371 WP_336512685.1 bacteriocin secretion accessory protein Regulator
  L6411_RS00375 (GUT189_00550) ruvB 58337..59335 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  L6411_RS00380 (GUT189_00560) - 59507..60130 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  L6411_RS00385 (GUT189_00570) comR 60233..61135 (+) 903 WP_155966071.1 helix-turn-helix domain-containing protein Regulator
  L6411_RS00390 (GUT189_00580) - 61337..62563 (+) 1227 WP_237374189.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50651.30 Da        Isoelectric Point: 5.7393

>NTDB_id=91211 L6411_RS00370 WP_336512685.1 56536..57906(+) (comB) [Streptococcus ruminantium strain GUT-189]
MMEHQLLESGEFYHRRYHNAASRVILPSFALLVFLMMFAFFAKKELTVVTRATVEPLHVLSKIQSTSNNPIKMNYLKENQ
EVAVGDVLVEYQSSSEQIQEEGIKKKITLLKEQLSQLELLKKSLESGENQFPQEDKYGYSQTFVDYRNKLLTLESNVEQQ
NTTIAAQNAAISQSQMELGNIVKTSQKALSDYKNLRMAIQSDAEISEDNAGYSLYVGYTTQLSQATGIAEKTTLKQQMLT
QVDNQISQLENQLATYRVQYAGAGAQQAYATNLDSQSASLKSQYLTKVAQEWTSLSSQLGELEGTLGLQENMRAKTKIVA
NQAGIIHLNSEVEGTSMIAEGTVIAHIYPSLAEIKKVKVTAYVSSKDVASLSEGDVIHFSAQASQAGQIRLTSTITSIAT
SATKTEAGNFFKIEAETDLSKTFAEKIRYGLEGKFVVITGEKTYFQYIVDEFLGKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=91211 L6411_RS00370 WP_336512685.1 56536..57906(+) (comB) [Streptococcus ruminantium strain GUT-189]
ATGATGGAACATCAGCTATTAGAGAGTGGGGAATTTTACCATCGGCGTTATCATAATGCGGCAAGTAGAGTTATATTGCC
AAGTTTTGCTTTATTAGTCTTTTTGATGATGTTTGCCTTCTTTGCTAAGAAAGAACTGACGGTAGTGACTCGAGCAACTG
TTGAGCCACTTCATGTTTTATCCAAAATTCAATCCACAAGCAACAATCCTATTAAGATGAATTATTTGAAAGAAAATCAG
GAAGTTGCTGTGGGTGATGTTTTGGTTGAATATCAGTCTTCCAGTGAGCAGATTCAAGAAGAAGGTATTAAGAAAAAAAT
TACTCTGTTAAAGGAGCAATTATCTCAGCTTGAACTGTTGAAAAAGAGTTTAGAATCGGGAGAAAACCAGTTTCCTCAAG
AGGATAAGTATGGTTATTCACAAACCTTTGTTGATTATCGAAATAAATTATTGACATTGGAGAGCAATGTAGAGCAGCAG
AATACCACGATTGCTGCTCAGAATGCAGCTATTAGTCAATCGCAGATGGAATTAGGTAATATAGTCAAAACCAGTCAAAA
GGCATTGTCAGATTATAAGAATCTCAGAATGGCCATTCAATCTGACGCTGAAATTTCTGAGGATAATGCAGGTTATTCAC
TCTATGTGGGATATACAACTCAATTATCTCAAGCAACTGGTATAGCTGAAAAAACAACTCTTAAACAGCAGATGTTAACG
CAGGTAGATAACCAAATTAGTCAATTAGAAAATCAGTTGGCTACTTATCGGGTACAGTATGCTGGGGCGGGAGCTCAACA
AGCCTATGCCACTAATTTAGATAGTCAGTCTGCATCGCTCAAATCCCAATATTTGACCAAGGTCGCCCAAGAGTGGACTT
CTCTATCAAGTCAATTAGGTGAACTTGAAGGGACATTGGGGTTACAAGAAAATATGAGAGCTAAGACAAAGATTGTAGCC
AATCAAGCAGGAATTATTCATCTAAATAGTGAAGTTGAGGGAACATCTATGATTGCAGAAGGTACGGTCATTGCTCACAT
TTATCCGAGTTTGGCTGAGATTAAAAAGGTAAAAGTTACCGCCTATGTATCCTCGAAAGATGTTGCCAGCCTGTCTGAGG
GAGATGTGATTCATTTTTCTGCTCAAGCTAGTCAAGCAGGACAGATTCGCCTGACTTCTACCATCACTTCTATTGCAACC
AGTGCGACCAAGACAGAAGCAGGAAATTTCTTTAAGATTGAAGCGGAGACAGACTTATCAAAAACATTTGCTGAGAAAAT
ACGGTATGGATTAGAAGGGAAATTTGTGGTAATTACAGGGGAGAAGACTTATTTTCAGTATATTGTAGATGAATTTTTAG
GGAAAAAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(318-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

51.77

99.123

0.513
  comB Streptococcus pneumoniae Rx1

50.11

99.781

0.5
  comB Streptococcus pneumoniae D39

50.11

99.781

0.5
  comB Streptococcus pneumoniae R6

50.11

99.781

0.5
  comB Streptococcus pneumoniae TIGR4

49.89

99.781

0.498
  comB Streptococcus mitis SK321

49.89

99.781

0.498
  comB Streptococcus mitis NCTC 12261

49.451

99.781

0.493

Multiple sequence alignment