Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   L6411_RS00385 Genome accession   NZ_AP025333
Coordinates   60233..61135 (+) Length   300 a.a.
NCBI ID   WP_155966071.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-189     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 55233..66135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6411_RS00370 (GUT189_00540) comB 56536..57906 (+) 1371 WP_336512685.1 bacteriocin secretion accessory protein Regulator
  L6411_RS00375 (GUT189_00550) ruvB 58337..59335 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  L6411_RS00380 (GUT189_00560) - 59507..60130 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  L6411_RS00385 (GUT189_00570) comR 60233..61135 (+) 903 WP_155966071.1 helix-turn-helix domain-containing protein Regulator
  L6411_RS00390 (GUT189_00580) - 61337..62563 (+) 1227 WP_237374189.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  L6411_RS00395 (GUT189_00590) - 62765..64264 (+) 1500 WP_155962533.1 quinol oxidase -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35651.81 Da        Isoelectric Point: 4.6520

>NTDB_id=91212 L6411_RS00385 WP_155966071.1 60233..61135(+) (comR) [Streptococcus ruminantium strain GUT-189]
MDNKEFGQRVRQLREQAMITREQFCDDEMELSVRQLTRIEAGTCKPTFSKINFIADRLGMGLYELMPDYIKLPERYSKLK
FDVLRTPTYGNEGLVETRNEMITEIYEEYYDDLPEEEQIAMDAFQSRLDTLESGVEGFGKEILEDYFEQVFRKPKYEVND
LLIIRLHLEYVRLADRNSEIFLHFLGLIEELHKQIDVVSAGDLFVLRDTLLSCVNILGSKKYYEPILKIFDSVDKITQLT
QDFQKKPIISLMKWKYALFVTKDRKEAERHYQEAKLFSQLIENEILKQKIDEEWKTDTQQ

Nucleotide


Download         Length: 903 bp        

>NTDB_id=91212 L6411_RS00385 WP_155966071.1 60233..61135(+) (comR) [Streptococcus ruminantium strain GUT-189]
ATGGATAATAAGGAATTTGGTCAGCGTGTACGGCAACTACGAGAACAAGCAATGATAACACGAGAACAGTTTTGTGATGA
TGAAATGGAACTCTCTGTTCGTCAGTTAACTCGGATTGAGGCTGGTACCTGTAAACCAACATTTTCTAAGATAAATTTTA
TCGCTGATCGTTTGGGGATGGGTCTATATGAACTAATGCCAGATTACATCAAACTACCAGAGAGATATTCAAAATTGAAA
TTTGATGTTCTGCGAACGCCTACATATGGGAATGAGGGATTGGTAGAAACACGTAACGAAATGATCACGGAAATTTATGA
AGAGTATTATGATGACTTGCCAGAAGAAGAACAAATAGCAATGGATGCTTTTCAATCGCGTCTTGACACACTGGAATCAG
GTGTTGAGGGATTTGGTAAAGAAATATTAGAAGACTATTTTGAACAAGTGTTTCGTAAACCTAAGTATGAAGTAAATGAT
TTATTAATTATTCGACTTCATCTTGAATACGTACGACTTGCGGATCGTAACTCGGAGATATTTCTTCATTTTCTGGGTCT
CATTGAAGAGTTACATAAACAGATTGATGTAGTTAGTGCAGGTGATCTGTTCGTTTTGCGTGATACATTACTATCTTGTG
TGAACATATTGGGTAGCAAAAAATATTATGAACCTATTCTAAAGATATTCGATAGTGTGGATAAAATTACACAGTTAACA
CAGGATTTTCAAAAAAAGCCCATTATTAGCTTGATGAAATGGAAATATGCTCTTTTTGTTACAAAAGATAGAAAAGAAGC
TGAGCGGCATTATCAAGAAGCGAAATTATTTTCCCAGTTAATAGAAAATGAGATTTTAAAGCAGAAAATTGATGAGGAAT
GGAAAACTGATACCCAACAATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

76.589

99.667

0.763
  comR Streptococcus suis 05ZYH33

76.589

99.667

0.763
  comR Streptococcus suis D9

56.478

100

0.567
  comR Streptococcus mutans UA159

43

100

0.43
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.931

96

0.383
  comR Streptococcus pyogenes MGAS315

37.584

99.333

0.373

Multiple sequence alignment