Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   U0447_RS07950 Genome accession   NZ_CP139861
Coordinates   1525802..1527478 (-) Length   558 a.a.
NCBI ID   WP_306423909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1520802..1532478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS07920 - 1521137..1521466 (-) 330 WP_000132569.1 hypothetical protein -
  U0447_RS07925 - 1521742..1522080 (+) 339 WP_000682124.1 LytTR family DNA-binding domain-containing protein -
  U0447_RS07930 comE/blpR 1522085..1522822 (+) 738 WP_001219139.1 response regulator transcription factor Regulator
  U0447_RS07935 - 1522836..1524176 (+) 1341 WP_001017622.1 sensor histidine kinase -
  U0447_RS07940 blpC 1524218..1524373 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  U0447_RS07945 - 1524430..1525791 (-) 1362 Protein_1516 bacteriocin secretion accessory protein -
  U0447_RS07950 comA/nlmT 1525802..1527478 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  U0447_RS07955 comA/nlmT 1527372..1527959 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  U0447_RS07960 blpU 1528240..1528470 (+) 231 WP_001093268.1 bacteriocin-like peptide BlpU -
  U0447_RS07965 - 1528473..1528592 (+) 120 WP_001829206.1 PncF family bacteriocin immunity protein -
  U0447_RS07970 - 1529061..1529432 (+) 372 WP_033705507.1 hypothetical protein -
  U0447_RS07975 - 1530061..1530444 (+) 384 WP_016398494.1 hypothetical protein -
  U0447_RS07980 - 1530496..1531185 (+) 690 WP_050201633.1 CPBP family intramembrane glutamic endopeptidase -
  U0447_RS07985 blpZ 1531227..1531460 (+) 234 WP_000276498.1 immunity protein BlpZ -
  U0447_RS07990 - 1531611..1532222 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62978.29 Da        Isoelectric Point: 7.1280

>NTDB_id=911442 U0447_RS07950 WP_306423909.1 1525802..1527478(-) (comA/nlmT) [Streptococcus pneumoniae strain 16H2017-2]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=911442 U0447_RS07950 WP_306423909.1 1525802..1527478(-) (comA/nlmT) [Streptococcus pneumoniae strain 16H2017-2]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667