Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   U0447_RS07955 Genome accession   NZ_CP139861
Coordinates   1527372..1527959 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain 16H2017-2     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1522372..1532959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0447_RS07935 - 1522836..1524176 (+) 1341 WP_001017622.1 sensor histidine kinase -
  U0447_RS07940 blpC 1524218..1524373 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  U0447_RS07945 - 1524430..1525791 (-) 1362 Protein_1516 bacteriocin secretion accessory protein -
  U0447_RS07950 comA/nlmT 1525802..1527478 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  U0447_RS07955 comA/nlmT 1527372..1527959 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  U0447_RS07960 blpU 1528240..1528470 (+) 231 WP_001093268.1 bacteriocin-like peptide BlpU -
  U0447_RS07965 - 1528473..1528592 (+) 120 WP_001829206.1 PncF family bacteriocin immunity protein -
  U0447_RS07970 - 1529061..1529432 (+) 372 WP_033705507.1 hypothetical protein -
  U0447_RS07975 - 1530061..1530444 (+) 384 WP_016398494.1 hypothetical protein -
  U0447_RS07980 - 1530496..1531185 (+) 690 WP_050201633.1 CPBP family intramembrane glutamic endopeptidase -
  U0447_RS07985 blpZ 1531227..1531460 (+) 234 WP_000276498.1 immunity protein BlpZ -
  U0447_RS07990 - 1531611..1532222 (+) 612 WP_000394036.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=911443 U0447_RS07955 WP_000205166.1 1527372..1527959(-) (comA/nlmT) [Streptococcus pneumoniae strain 16H2017-2]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=911443 U0447_RS07955 WP_000205166.1 1527372..1527959(-) (comA/nlmT) [Streptococcus pneumoniae strain 16H2017-2]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497