Detailed information NTG0911373

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: U0448_RS09765
• Genome accession: NZ_CP139860
• Coordinates: 1914007..1914855 (+)
• Length: 282 a.a.
• NCBI ID: WP_044727471.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21011
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1909007..1919855

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0448_RS09740	-	1909722..1910429 (+)	708	WP_000638482.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
U0448_RS09745	-	1910434..1911456 (+)	1023	WP_000609888.1	ribitol-5-phosphate dehydrogenase	-
U0448_RS09750	licA	1911473..1912342 (+)	870	WP_000411207.1	choline kinase LicA	-
U0448_RS09755	-	1912332..1913210 (+)	879	WP_000837609.1	DMT family transporter	-
U0448_RS09760	-	1913222..1913911 (+)	690	WP_044727470.1	CTP--phosphocholine cytidylyltransferase	-
U0448_RS09765	dprA/cilB/dalA	1914007..1914855 (+)	849	WP_044727471.1	DNA-processing protein DprA	Machinery gene
U0448_RS09770	-	1915039..1915161 (-)	123	WP_257881851.1	hypothetical protein	-
U0448_RS09775	-	1915739..1916782 (+)	1044	WP_219576793.1	TIGR00341 family protein	-
U0448_RS09780	topA	1916949..1919036 (+)	2088	WP_000179638.1	type I DNA topoisomerase	-
U0448_RS09785	-	1919142..1919501 (+)	360	WP_044791349.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31066.71 Da
• Isoelectric Point: 5.4047

>NTDB_id=911373 U0448_RS09765 WP_044727471.1 1914007..1914855(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 21011]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLLLSEYGSGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=911373 U0448_RS09765 WP_044727471.1 1914007..1914855(+) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 21011]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTTTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGCTTCTCAGTGAATATGGATCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	63.571	99.291	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.102	100	0.372
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362