Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   U0448_RS07740 Genome accession   NZ_CP139860
Coordinates   1509977..1510990 (-) Length   337 a.a.
NCBI ID   WP_307772067.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1504977..1515990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS07710 - 1505250..1505588 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  U0448_RS07715 comE/blpR 1505593..1506330 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  U0448_RS07720 - 1506344..1507684 (+) 1341 WP_050258907.1 sensor histidine kinase -
  U0448_RS07725 blpC 1507712..1507885 (-) 174 WP_050258908.1 quorum-sensing system pheromone BlpC -
  U0448_RS07730 - 1507942..1509303 (-) 1362 WP_042516064.1 bacteriocin secretion accessory protein -
  U0448_RS07735 comA/nlmT 1509314..1509961 (-) 648 WP_078102557.1 ATP-binding cassette domain-containing protein Regulator
  U0448_RS07740 comA/nlmT 1509977..1510990 (-) 1014 WP_307772067.1 ABC transporter transmembrane domain-containing protein Regulator
  U0448_RS07745 comA/nlmT 1510884..1511471 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  U0448_RS07750 blpI 1511753..1511950 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  U0448_RS07755 blpJ 1512417..1512686 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  U0448_RS07760 blpU 1512755..1512985 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  U0448_RS07765 - 1512988..1513107 (+) 120 WP_050079265.1 PncF family bacteriocin immunity protein -
  U0448_RS07770 - 1513893..1514276 (+) 384 WP_000877381.1 hypothetical protein -
  U0448_RS07775 - 1514328..1515017 (+) 690 WP_050258910.1 CPBP family intramembrane glutamic endopeptidase -
  U0448_RS07780 blpZ 1515059..1515292 (+) 234 WP_000276498.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 337 a.a.        Molecular weight: 38280.73 Da        Isoelectric Point: 5.1196

>NTDB_id=911365 U0448_RS07740 WP_307772067.1 1509977..1510990(-) (comA/nlmT) [Streptococcus pneumoniae strain 21011]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFG

Nucleotide


Download         Length: 1014 bp        

>NTDB_id=911365 U0448_RS07740 WP_307772067.1 1509977..1510990(-) (comA/nlmT) [Streptococcus pneumoniae strain 21011]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGATTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGATGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.997

100

0.73
  comA Streptococcus gordonii str. Challis substr. CH1

67.16

100

0.674
  comA Streptococcus mitis NCTC 12261

66.766

100

0.668
  comA Streptococcus pneumoniae Rx1

66.469

100

0.665
  comA Streptococcus pneumoniae D39

66.469

100

0.665
  comA Streptococcus pneumoniae R6

66.469

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.172

100

0.662
  comA Streptococcus mitis SK321

66.172

100

0.662