Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   U0448_RS00795 Genome accession   NZ_CP139860
Coordinates   162828..163478 (-) Length   216 a.a.
NCBI ID   WP_001863003.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 157828..168478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS00775 - 158430..159614 (-) 1185 WP_081570984.1 hypothetical protein -
  U0448_RS00780 - 159618..160205 (-) 588 WP_000933542.1 ATP-binding cassette domain-containing protein -
  U0448_RS00785 - 160237..160425 (-) 189 WP_023396236.1 hypothetical protein -
  U0448_RS00790 comEC/celB 160604..162844 (-) 2241 WP_219576836.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  U0448_RS00795 comEA/celA/cilE 162828..163478 (-) 651 WP_001863003.1 ComEA family DNA-binding protein Machinery gene
  U0448_RS00800 - 163546..164115 (-) 570 WP_050102500.1 GNAT family N-acetyltransferase -
  U0448_RS00805 ald 164292..165403 (+) 1112 Protein_160 alanine dehydrogenase -
  U0448_RS00810 - 165704..166029 (-) 326 Protein_161 TfoX/Sxy family protein -
  U0448_RS00815 - 166032..166532 (-) 501 WP_050091289.1 GNAT family N-acetyltransferase -
  U0448_RS00820 - 166725..167693 (-) 969 WP_000658198.1 PhoH family protein -
  U0448_RS00825 - 167779..167994 (-) 216 WP_001232082.1 YozE family protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23215.62 Da        Isoelectric Point: 5.5171

>NTDB_id=911302 U0448_RS00795 WP_001863003.1 162828..163478(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 21011]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=911302 U0448_RS00795 WP_001863003.1 162828..163478(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain 21011]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae D39

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae R6

99.537

100

0.995
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.759

100

0.968
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

90.741

100

0.907
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361