Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   SUT_RS00380 Genome accession   NZ_AP025331
Coordinates   59222..60592 (+) Length   456 a.a.
NCBI ID   WP_336512693.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 54222..65592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS00350 (GUT183_00510) - 54354..54506 (+) 153 WP_237373294.1 hypothetical protein -
  SUT_RS10215 - 55162..55293 (+) 132 WP_257875343.1 hypothetical protein -
  SUT_RS00355 (GUT183_00520) - 55503..55697 (+) 195 WP_024533168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SUT_RS00360 (GUT183_00540) - 55903..56058 (+) 156 WP_024533167.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SUT_RS00365 (GUT183_00550) - 56113..56304 (+) 192 WP_024533166.1 hypothetical protein -
  SUT_RS00370 - 56570..56716 (+) 147 WP_155962530.1 hypothetical protein -
  SUT_RS00375 (GUT183_00560) comA 57063..59216 (+) 2154 WP_120171173.1 peptide cleavage/export ABC transporter ComA Regulator
  SUT_RS00380 (GUT183_00570) comB 59222..60592 (+) 1371 WP_336512693.1 bacteriocin secretion accessory protein Regulator
  SUT_RS00385 (GUT183_00580) ruvB 61024..62022 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  SUT_RS00390 (GUT183_00590) - 62193..62816 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  SUT_RS00395 (GUT183_00600) comR 62919..63818 (+) 900 WP_024532318.1 helix-turn-helix domain-containing protein Regulator
  SUT_RS00400 (GUT183_00610) - 64034..65260 (+) 1227 WP_237373295.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 50601.28 Da        Isoelectric Point: 5.5485

>NTDB_id=91104 SUT_RS00380 WP_336512693.1 59222..60592(+) (comB) [Streptococcus ruminantium strain GUT-183]
MMEYQLLESGEFYHRRYHNAASRVILPSFALLVFLMMFAFFAKKELTVVTRATVEPLHVLSKIQSTSNNPIKMNYLKENQ
EVAVGDVLVEYQSSSEQIQEEGIKKKITLLKEQLSQLELLKKSLESGENQFPQEDKYGYSQTFVDYRNKLLTLESNVEQQ
NTTIAAQNAAISQSQMELGNIVKTSQKALSDYKNLRMAIQSDAEISEDNAGYSLYVGYTTQLSQATGIAEKTTLKQQMLT
QVDNQISQLENQLATYRVQYAGAGAQQAYATNLDSQSASLKSQYLTKVAQEWTSLSSQLGELEGTLGLQENMRAKTKIVA
NQAGIIHLNSEVEGASMIAEGTIIAHIYPSLAEIKKVKVTAYVSSKDVASLSEGDVIHFSAQASQAGQIRLTSTITSIAT
SATKTEAGNFFKIEAEADLSKAFAEKIRYGLEGKFVVITGEKTYFQYIVDEFLGKK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=91104 SUT_RS00380 WP_336512693.1 59222..60592(+) (comB) [Streptococcus ruminantium strain GUT-183]
ATGATGGAATATCAGCTATTAGAGAGTGGGGAATTTTACCATCGGCGTTATCATAATGCGGCAAGTAGAGTTATATTGCC
AAGTTTTGCTTTATTAGTCTTTTTGATGATGTTTGCCTTCTTTGCTAAGAAAGAACTGACGGTAGTGACTCGAGCAACTG
TTGAGCCACTTCATGTTTTATCCAAAATTCAATCCACAAGCAACAATCCTATTAAGATGAATTATTTGAAAGAAAATCAG
GAAGTTGCTGTGGGTGATGTTTTGGTTGAATATCAGTCTTCCAGTGAGCAGATTCAAGAAGAAGGTATTAAGAAAAAAAT
TACTCTGTTAAAGGAGCAATTATCTCAGCTTGAACTGTTGAAAAAGAGTTTAGAATCGGGAGAAAACCAGTTTCCTCAAG
AGGATAAGTATGGTTATTCACAAACCTTTGTTGATTATCGAAATAAATTATTGACATTGGAGAGCAATGTAGAGCAGCAG
AATACCACGATTGCTGCTCAGAATGCAGCTATTAGTCAATCGCAGATGGAATTAGGTAATATAGTCAAAACCAGTCAAAA
GGCATTGTCAGATTATAAGAATCTCAGAATGGCCATTCAATCTGACGCTGAAATTTCTGAGGATAATGCAGGTTATTCAC
TCTATGTGGGATATACAACTCAATTATCACAAGCAACTGGTATAGCTGAAAAAACAACTCTTAAACAGCAGATGTTAACG
CAGGTAGATAACCAAATTAGTCAATTAGAAAATCAGTTGGCTACTTATCGGGTACAGTATGCTGGGGCGGGAGCTCAACA
AGCCTATGCCACTAATTTAGATAGTCAGTCTGCATCGCTCAAATCCCAATATTTGACCAAGGTCGCCCAAGAGTGGACTT
CTCTATCAAGTCAATTAGGTGAACTTGAAGGGACATTGGGGTTACAAGAAAATATGAGAGCTAAGACAAAGATTGTAGCC
AATCAAGCAGGAATTATTCATCTAAATAGTGAAGTTGAGGGAGCATCTATGATTGCAGAAGGTACGATCATTGCTCACAT
TTATCCGAGTTTGGCTGAGATTAAAAAGGTAAAAGTTACCGCCTATGTATCCTCGAAAGATGTTGCCAGCCTGTCTGAGG
GAGATGTGATTCATTTTTCTGCTCAAGCTAGTCAAGCAGGACAGATTCGCCTGACTTCTACCATCACTTCTATTGCAACC
AGTGCGACCAAGACAGAAGCAGGAAATTTCTTTAAGATTGAAGCGGAGGCAGACTTATCAAAAGCATTTGCTGAGAAAAT
ACGGTATGGATTAGAAGGGAAATTTGTGGTAATTACAGGGGAGAAGACTTATTTTCAGTATATTGTAGATGAATTTTTAG
GAAAAAAATAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(318-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

51.77

99.123

0.513
  comB Streptococcus pneumoniae Rx1

49.89

99.781

0.498
  comB Streptococcus pneumoniae D39

49.89

99.781

0.498
  comB Streptococcus pneumoniae R6

49.89

99.781

0.498
  comB Streptococcus pneumoniae TIGR4

49.67

99.781

0.496
  comB Streptococcus mitis SK321

49.67

99.781

0.496
  comB Streptococcus mitis NCTC 12261

49.231

99.781

0.491

Multiple sequence alignment