Detailed information NTG0091103

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: SUT_RS00375
• Genome accession: NZ_AP025331
• Coordinates: 57063..59216 (+)
• Length: 717 a.a.
• NCBI ID: WP_120171173.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-183
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 52063..64216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUT_RS00330 (GUT183_00470)	-	53090..53299 (+)	210	WP_237373290.1	hypothetical protein	-
SUT_RS00335 (GUT183_00480)	-	53352..53540 (+)	189	WP_024533071.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SUT_RS00340 (GUT183_00490)	-	53750..53932 (+)	183	WP_237373291.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SUT_RS00345 (GUT183_00500)	-	54034..54189 (+)	156	WP_237373293.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SUT_RS00350 (GUT183_00510)	-	54354..54506 (+)	153	WP_237373294.1	hypothetical protein	-
SUT_RS10215	-	55162..55293 (+)	132	WP_257875343.1	hypothetical protein	-
SUT_RS00355 (GUT183_00520)	-	55503..55697 (+)	195	WP_024533168.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SUT_RS00360 (GUT183_00540)	-	55903..56058 (+)	156	WP_024533167.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SUT_RS00365 (GUT183_00550)	-	56113..56304 (+)	192	WP_024533166.1	hypothetical protein	-
SUT_RS00370	-	56570..56716 (+)	147	WP_155962530.1	hypothetical protein	-
SUT_RS00375 (GUT183_00560)	comA	57063..59216 (+)	2154	WP_120171173.1	peptide cleavage/export ABC transporter ComA	Regulator
SUT_RS00380 (GUT183_00570)	comB	59222..60592 (+)	1371	WP_336512693.1	bacteriocin secretion accessory protein	Regulator
SUT_RS00385 (GUT183_00580)	ruvB	61024..62022 (+)	999	WP_024532316.1	Holliday junction branch migration DNA helicase RuvB	-
SUT_RS00390 (GUT183_00590)	-	62193..62816 (+)	624	WP_155962542.1	HAD-IA family hydrolase	-
SUT_RS00395 (GUT183_00600)	comR	62919..63818 (+)	900	WP_024532318.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80966.11 Da
• Isoelectric Point: 7.0769

>NTDB_id=91103 SUT_RS00375 WP_120171173.1 57063..59216(+) (comA) [Streptococcus ruminantium strain GUT-183]
MKFRKRHYRAQVDTRDCGVAALAMILEYHHSHHSLASLRELAKTTMEGTTAFGLVKVAEDLGLETRAIRADMSLFEVGDL
TYPFIAHVLKDGKLMHYYVVTGADEKTIHIADPDPSVKLTKLTRERFEQEWTGVSLFMAPRPEYQPHKEKKQGLLSFVPL
LAKQKRLIGNIILATLLVTLINIVGSYYLQSIIDTYVPNQMKTTLGVISIGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIILIISVVLFSQNIYLFFIALLSLPIYSV
IIFAFMKPFERMNQEVMETNAVLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVDYLKKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGATLVMDNKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTARVANNRLNEVYLVESEFADQKTVTDLSLV
SGDIDFRDVSYKYGYGADVLSDINLTIKRGEKISFVGVSGSGKTTLAKMMVNFYDPYKGEINLNNVNLNQIDKHALRQHI
NYLPQQPYIFNGTILENLLLGAKEGTTQEDVLRAVEIACIREDIEKMPLNYQTELTSDGSGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLALDKTLIFIVHRLTIAERTERVVVLDKGKIVEQGCHRELLDQQGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=91103 SUT_RS00375 WP_120171173.1 57063..59216(+) (comA) [Streptococcus ruminantium strain GUT-183]
ATGAAGTTTAGGAAACGGCATTATAGGGCTCAGGTGGATACACGAGATTGTGGTGTAGCCGCTCTTGCAATGATTTTGGA
GTACCATCATTCTCATCATTCTTTGGCAAGTCTTCGAGAACTGGCTAAAACAACCATGGAAGGAACGACAGCATTTGGAC
TAGTTAAAGTAGCTGAAGACTTGGGGCTTGAAACTCGCGCAATTCGAGCAGATATGTCCTTATTTGAGGTGGGAGATTTA
ACTTATCCCTTCATAGCTCATGTACTGAAAGATGGCAAGCTCATGCACTACTACGTTGTTACGGGTGCGGATGAGAAGAC
CATCCATATTGCAGATCCAGATCCTTCGGTCAAGTTAACTAAGTTAACTCGTGAACGATTTGAACAGGAATGGACAGGGG
TATCCTTATTCATGGCTCCTAGACCGGAATATCAACCTCACAAAGAGAAGAAGCAAGGCTTGTTGTCTTTTGTTCCCTTG
CTGGCAAAGCAAAAGAGATTGATTGGCAATATTATTTTGGCTACTCTTTTGGTGACGCTCATCAATATTGTTGGATCTTA
TTATCTACAATCCATCATTGATACCTATGTTCCAAATCAGATGAAGACAACTTTGGGAGTTATCTCAATTGGTTTAGTTG
TGGTGTATGCCTTGCAACAGTTGCTGTCTTACGCACAAGAGTATCTGCTCATTATACTGGGGCAAAGACTATCTATAGAT
GTTATCCTATCTTATATCAGACATGTATTCCATTTGCCAATGTCTTTTTTTGCAACACGGCGCACAGGGGAAATCGTTTC
TCGCTTTACAGATGCAAACTCTATTATTGATGCTTTGGCAAGTACAATTCTATCTATTTTCTTAGATGTATCCATTATTT
TGATTATTTCGGTTGTCTTATTTAGTCAGAATATTTACTTGTTTTTTATAGCTTTGTTGTCATTGCCGATTTATTCTGTC
ATTATTTTTGCATTTATGAAGCCATTTGAACGCATGAATCAGGAAGTAATGGAAACAAATGCTGTTTTGTCTTCTTCTAT
TATTGAAGACATCAATGGCATTGAAACAATTAAATCATTGACCAGTGAAAAACAACGTTATCAGAAAATTGATAAAGAAT
TTGTAGACTATCTGAAAAAATCTTTTGCCTATAACAAGGCAGAAGGACAACAAAAAGTGTTAAAGCGCTTGGCTCAGCTA
GTGCTGAACGTGGCTATTTTGTGGTTGGGAGCAACTCTCGTCATGGACAATAAGATGACGCTCGGTCAGCTCATCACGTT
CAATACCTTATTGGTCTACTTCACTAATCCTCTGGAAAATATTATCAATCTACAAACAAAACTTCAAACAGCTCGTGTAG
CAAATAATCGTCTCAATGAAGTTTATTTAGTTGAATCTGAGTTTGCGGATCAAAAGACAGTCACTGACTTGTCCCTGGTT
TCAGGAGATATTGATTTTAGAGATGTTAGTTATAAATATGGGTATGGTGCAGATGTCTTGTCAGACATCAATTTGACAAT
CAAGCGTGGTGAGAAGATTTCTTTTGTCGGAGTTTCTGGATCTGGTAAAACAACGCTGGCCAAGATGATGGTAAATTTTT
ATGATCCTTATAAGGGGGAGATTAACTTGAACAATGTAAATCTCAACCAAATTGACAAGCATGCTTTGCGTCAGCACATC
AATTACTTACCACAACAACCCTATATTTTTAATGGAACTATTTTAGAGAATCTCTTGCTAGGTGCCAAAGAGGGGACCAC
TCAGGAGGATGTCTTGCGAGCAGTAGAAATTGCCTGCATCAGAGAAGACATTGAAAAAATGCCTCTGAATTATCAGACGG
AGCTGACATCGGATGGATCAGGTATATCGGGTGGTCAACGCCAGCGCATCGCTCTGGCTCGAGCGTTGTTGACAGATGCT
CCGATTATGATTTTGGATGAGGCTACCAGTAGTTTAGACATCCTGACGGAGAAGCGAATTGTTGATAATTTGCTCGCCTT
GGATAAGACATTGATTTTTATTGTTCATCGTCTAACCATTGCGGAACGAACAGAGCGTGTCGTTGTACTTGATAAGGGAA
AAATTGTGGAACAAGGTTGTCATAGAGAACTACTCGATCAACAGGGATTTTATGCACATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	81.172	100	0.812
comA	Streptococcus pneumoniae Rx1	81.032	100	0.81
comA	Streptococcus pneumoniae D39	81.032	100	0.81
comA	Streptococcus pneumoniae R6	81.032	100	0.81
comA	Streptococcus mitis SK321	80.893	100	0.809
comA	Streptococcus pneumoniae TIGR4	80.753	100	0.808
comA	Streptococcus gordonii str. Challis substr. CH1	78.103	100	0.781
comA/nlmT	Streptococcus mutans UA159	63.877	100	0.639