Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SUT_RS00395 Genome accession   NZ_AP025331
Coordinates   62919..63818 (+) Length   299 a.a.
NCBI ID   WP_024532318.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-183     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57919..68818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUT_RS00380 (GUT183_00570) comB 59222..60592 (+) 1371 WP_336512693.1 bacteriocin secretion accessory protein Regulator
  SUT_RS00385 (GUT183_00580) ruvB 61024..62022 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  SUT_RS00390 (GUT183_00590) - 62193..62816 (+) 624 WP_155962542.1 HAD-IA family hydrolase -
  SUT_RS00395 (GUT183_00600) comR 62919..63818 (+) 900 WP_024532318.1 helix-turn-helix domain-containing protein Regulator
  SUT_RS00400 (GUT183_00610) - 64034..65260 (+) 1227 WP_237373295.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  SUT_RS00405 (GUT183_00620) - 65462..66961 (+) 1500 WP_237373296.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35655.74 Da        Isoelectric Point: 4.4700

>NTDB_id=91105 SUT_RS00395 WP_024532318.1 62919..63818(+) (comR) [Streptococcus ruminantium strain GUT-183]
MDNKEFGQRVRQLREQAMITREQFCDDEMELSVRQLTRIEAGTCKPTFSKINFIADRLGMGLYELMPDYIKLPERYSKLK
FDVLRTPTYGNEGLVETRNEMITEIYEEYYDDLPEEEQIAMDAFQSIIDVFETKSTQYGREILDDYFEQVYRKEKYTIND
LLILRLYLEHIRFEETSSQMFQIFLDMVKHFPNQTEAIDPGDLFIFRDIMLTSIGILGTKEQFGYIPVLFDTLDKLMMST
QDFQKKPILNLLKWKYELRIHGNKERAREFYEEAVLFAKMIASPHLAEKLEEEWANDSQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=91105 SUT_RS00395 WP_024532318.1 62919..63818(+) (comR) [Streptococcus ruminantium strain GUT-183]
ATGGATAATAAGGAATTTGGTCAGCGTGTACGGCAACTACGAGAACAAGCAATGATAACACGAGAACAGTTTTGTGATGA
TGAAATGGAACTCTCTGTTCGTCAGTTAACTCGGATTGAGGCTGGTACCTGTAAACCAACATTTTCTAAGATAAATTTTA
TCGCTGATCGTTTGGGGATGGGTCTATATGAACTAATGCCAGATTACATCAAACTACCAGAGAGATATTCAAAATTGAAA
TTTGATGTTCTGCGAACGCCTACATATGGGAATGAGGGATTGGTAGAAACACGTAACGAAATGATCACGGAAATTTATGA
AGAGTATTATGATGACTTGCCAGAAGAAGAACAAATAGCAATGGATGCTTTTCAATCCATTATTGACGTGTTTGAAACTA
AATCTACTCAATATGGTCGTGAAATATTGGATGACTATTTTGAACAAGTATATAGAAAAGAAAAATATACCATCAACGAT
TTATTGATTCTTAGGCTATACCTTGAGCACATAAGGTTCGAGGAAACCTCATCGCAAATGTTTCAGATTTTTTTGGATAT
GGTTAAGCATTTTCCAAATCAAACGGAAGCTATAGATCCGGGTGATTTATTCATATTCCGAGATATTATGCTTACTTCAA
TAGGGATATTAGGAACAAAAGAGCAATTTGGCTATATCCCTGTGTTATTTGATACACTGGATAAACTGATGATGTCTACT
CAAGATTTCCAAAAGAAACCAATTTTGAATCTTCTTAAGTGGAAATATGAACTGCGTATTCATGGGAATAAAGAACGTGC
ACGTGAGTTTTATGAAGAAGCAGTTCTGTTTGCGAAAATGATTGCAAGTCCTCACTTGGCTGAAAAATTAGAGGAGGAGT
GGGCTAACGATAGTCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

60.87

100

0.609
  comR Streptococcus suis 05ZYH33

60.87

100

0.609
  comR Streptococcus suis D9

58.472

100

0.589
  comR Streptococcus mutans UA159

38.127

100

0.381
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.31

96.99

0.381
  comR Streptococcus pyogenes MGAS8232

37.288

98.662

0.368

Multiple sequence alignment