Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SM123_RS03520 Genome accession   NZ_CP139419
Coordinates   765627..766328 (+) Length   233 a.a.
NCBI ID   WP_003008151.1    Uniprot ID   -
Organism   Streptococcus lingualis strain S5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 760627..771328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS03510 (SM123_03510) thrS 761921..763864 (+) 1944 WP_150906396.1 threonine--tRNA ligase -
  SM123_RS03515 (SM123_03515) - 764076..765125 (-) 1050 WP_320909832.1 DUF389 domain-containing protein -
  SM123_RS03520 (SM123_03520) micA 765627..766328 (+) 702 WP_003008151.1 response regulator YycF Regulator
  SM123_RS03525 (SM123_03525) micB 766321..767673 (+) 1353 WP_118227948.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SM123_RS03530 (SM123_03530) vicX 767681..768490 (+) 810 WP_049475139.1 MBL fold metallo-hydrolase Regulator
  SM123_RS03535 (SM123_03535) - 768917..769468 (+) 552 WP_320909833.1 hypothetical protein -
  SM123_RS03540 (SM123_03540) - 769502..769888 (+) 387 WP_320909834.1 YbaN family protein -
  SM123_RS03545 (SM123_03545) - 770005..771129 (-) 1125 WP_320909835.1 site-specific integrase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26690.49 Da        Isoelectric Point: 4.6027

>NTDB_id=909528 SM123_RS03520 WP_003008151.1 765627..766328(+) (micA) [Streptococcus lingualis strain S5]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDIIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENEADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=909528 SM123_RS03520 WP_003008151.1 765627..766328(+) (micA) [Streptococcus lingualis strain S5]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAAGGCTATGA
GGTATTGACAGCCTTTGATGGTCGGGAAGCTTTAGAGGTCTTTGCGGCTGAAAATCCGGATATTATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGCTTGGAAGTAGCGCGGACGATTCGTAAGACCAGCAATGTGCCGATCATTGTCCTATCTGCT
AAGGATACGGAATTTGATAAGGTCATCGGGCTTGAAATCGGGGCGGATGACTATGTAACCAAACCCTTCTCGAATCGGGA
ATTGCAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCTGAGTTTGCGGCTGATCCTCAGCTTGAAAATGAGGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCCTTCTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACCCAT
CGCGAATTTGAATTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACTCGTGAGCACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTAGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.957

98.712

0.365