Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SM123_RS03525 Genome accession   NZ_CP139419
Coordinates   766321..767673 (+) Length   450 a.a.
NCBI ID   WP_118227948.1    Uniprot ID   A0AAE8AGY1
Organism   Streptococcus lingualis strain S5     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 761321..772673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM123_RS03510 (SM123_03510) thrS 761921..763864 (+) 1944 WP_150906396.1 threonine--tRNA ligase -
  SM123_RS03515 (SM123_03515) - 764076..765125 (-) 1050 WP_320909832.1 DUF389 domain-containing protein -
  SM123_RS03520 (SM123_03520) micA 765627..766328 (+) 702 WP_003008151.1 response regulator YycF Regulator
  SM123_RS03525 (SM123_03525) micB 766321..767673 (+) 1353 WP_118227948.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SM123_RS03530 (SM123_03530) vicX 767681..768490 (+) 810 WP_049475139.1 MBL fold metallo-hydrolase Regulator
  SM123_RS03535 (SM123_03535) - 768917..769468 (+) 552 WP_320909833.1 hypothetical protein -
  SM123_RS03540 (SM123_03540) - 769502..769888 (+) 387 WP_320909834.1 YbaN family protein -
  SM123_RS03545 (SM123_03545) - 770005..771129 (-) 1125 WP_320909835.1 site-specific integrase -
  SM123_RS03550 (SM123_03550) - 771217..771522 (-) 306 WP_320909836.1 hypothetical protein -
  SM123_RS03555 (SM123_03555) - 771529..771906 (-) 378 WP_320909837.1 ImmA/IrrE family metallo-endopeptidase -
  SM123_RS03560 (SM123_03560) - 771903..772304 (-) 402 WP_320909838.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51115.30 Da        Isoelectric Point: 4.5649

>NTDB_id=909529 SM123_RS03525 WP_118227948.1 766321..767673(+) (micB) [Streptococcus lingualis strain S5]
MIDQLKQFVMSSNFVFVLITVGFIIVVALLLLENRRDNIKLRQLNAKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNVNPDEVLNTSILDLLSLGDDYDLRSLITEVPE
LTIDSQDENGEYISLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLEIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNILNNAIKYSPDGGKIKVGMKTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDWDTEEEE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=909529 SM123_RS03525 WP_118227948.1 766321..767673(+) (micB) [Streptococcus lingualis strain S5]
ATGATTGATCAACTAAAACAATTTGTAATGTCGTCGAACTTTGTCTTTGTTCTAATTACGGTTGGGTTTATCATTGTGGT
AGCCTTGCTTTTGTTAGAAAACCGTAGGGACAATATTAAGCTCAGACAATTAAACGCCAAAATTAAGGATCTGATTGCAG
GGGACTATTCTGAAGTGGTCGACATGCAAGGGAGTCCAGAACTGACAGATATGACCAATAGCATTAATGATCTGTCGGAG
GTTATTCGCCTGACGCATGAAAACTTGGAACAAGAAACCAAGCGTTTGACCAGTATCCTTTCTTACATGACAGACGGGGT
GCTTGCGACCAACAGACGTGGTCAGATCATCATGGTCAATGAAATGGCAGCCAAGCAATTGAATGTTAATCCAGATGAGG
TGCTTAATACCAGTATTCTGGATTTGCTTTCGCTTGGAGATGACTATGATCTGCGAAGCTTGATTACAGAAGTACCAGAG
TTGACCATCGATTCCCAGGATGAAAATGGGGAATACATAAGTCTTCGTGTGCGCTTTGCCTTGATTCGTCGCGAGTCAGG
TTTTATCTCTGGTCTGGTAGCTGTCTTGCACGATACGACAGAGCAGGACAAGGAAGAGCGGGAACGTCGCCTCTTTGTCT
CCAATGTGAGCCATGAATTGCGGACTCCCTTGACCAGTGTGAAATCCTATCTGGAAGCCCTAGACGATGGCGCTTTGTCA
GAGCCAGTAGCACCAGATTTTGTCAAGGTTTCACTCAATGAAACCAACCGCATGATGCGCATGGTCACAGATCTTTTGAG
TCTTTCTCGAATCGACAATGAAACTAGTCAGTTGGAGATCGAGTTGACCAACTTTACGGCCTTTATCACCTTTATTTTGA
ACCGCTTTGATAAGATCAAGAGTCAATCGCAAGAAGATACCAAGAAGTATGAACTGATCCGGGAATACCCGATCACTCCG
ATCTGGGTGGAAATTGATACGGATAAAATGACCCAGGTGATCGACAATATATTGAACAATGCCATCAAGTACTCACCTGA
TGGTGGAAAGATCAAGGTAGGGATGAAAACGACAGACGCCCAGTTGATTATCTCCATCTCAGATGAGGGCTTGGGGATTC
CCAAGAAAGACTTGCCGCGCATTTTTGATCGCTTTTACCGAGTGGATAAGGCACGTAGCCGGGCCCAAGGTGGGACTGGT
CTGGGCTTAGCCATTGCTAAGGAGATCGTTAAGCAACACAAAGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGATC
TACCTTTACCATTGTCTTGCCGTACGACAAAGATGCGATTAAAGACGACTGGGATACAGAAGAGGAAGAATAA

Domains

Predicted by InterProScan.

PAS fold (PAS)

(96-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.458

98

0.769
  vicK Streptococcus mutans UA159

71.253

90.444

0.644