Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SM121_RS05025 Genome accession   NZ_CP139418
Coordinates   1027730..1028431 (+) Length   233 a.a.
NCBI ID   WP_003005102.1    Uniprot ID   -
Organism   Streptococcus dentalis strain S1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1022730..1033431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM121_RS05015 (SM121_05015) thrS 1024024..1025967 (+) 1944 WP_320910524.1 threonine--tRNA ligase -
  SM121_RS05020 (SM121_05020) - 1026179..1027228 (-) 1050 WP_320910525.1 DUF389 domain-containing protein -
  SM121_RS05025 (SM121_05025) micA 1027730..1028431 (+) 702 WP_003005102.1 response regulator YycF Regulator
  SM121_RS05030 (SM121_05030) micB 1028424..1029776 (+) 1353 WP_003005638.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SM121_RS05035 (SM121_05035) vicX 1029784..1030593 (+) 810 WP_320910526.1 MBL fold metallo-hydrolase Regulator
  SM121_RS05040 (SM121_05040) - 1030713..1031099 (+) 387 WP_320910527.1 YbaN family protein -
  SM121_RS05045 (SM121_05045) - 1031351..1031812 (-) 462 WP_320910528.1 hypothetical protein -
  SM121_RS05050 (SM121_05050) rnc 1032146..1032847 (+) 702 WP_320910529.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26782.59 Da        Isoelectric Point: 4.7296

>NTDB_id=909488 SM121_RS05025 WP_003005102.1 1027730..1028431(+) (micA) [Streptococcus dentalis strain S1]
MKRILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFSAENPDVIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQFEKDADTEIVIGDLHILPDAFLVRKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=909488 SM121_RS05025 WP_003005102.1 1027730..1028431(+) (micA) [Streptococcus dentalis strain S1]
ATGAAAAGAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAGGGATATGA
AGTTTTAACGGCCTTTGATGGGCGGGAAGCTTTAGAAGTCTTTTCAGCTGAAAACCCAGATGTTATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGCTTGGAAGTGGCGCGGACGATTCGTAAGACCAGCAATGTGCCCATCATTGTCCTATCTGCT
AAGGATACGGAATTTGATAAGGTCATCGGGCTTGAAATCGGGGCGGATGACTATGTGACCAAACCTTTCTCTAATCGGGA
ATTACAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCGGAGTTTGCGGCTGATCCTCAGTTTGAAAAAGATGCCGATACAG
AAATTGTCATTGGCGATCTTCACATTCTTCCAGACGCTTTCTTGGTTCGAAAAGGCAACAAAGAATTGGACTTGACTCAT
CGCGAGTTTGAGTTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAACATCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACGGTGGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

100

0.815
  vicR Streptococcus mutans UA159

77.872

100

0.785
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.852

98.283

0.451
  covR Streptococcus salivarius strain HSISS4

44.105

98.283

0.433
  scnR Streptococcus mutans UA159

37.826

98.712

0.373